An analysis of the length of hospital stay after acetaminophen overdose

Human & Experimental Toxicology
Sa'ed H ZyoudSamah W Al-Jabi

Abstract

Acetaminophen is one of the most commonly encountered medications in self-poisoning, with a high rate of morbidity. The prevalence and characteristics of acetaminophen intoxication associated with long hospital stay in patients are not well defined. This study aims to identify the clinical and demographic factors associated with the length of in-hospital stay (LOS), and to evaluate the effect of early treatment of acetaminophen overdose patients (≤8 hours) by intravenous N-acetylcysteine (IV-NAC) on hospital stay. This is a retrospective cohort study of hospital admissions for acetaminophen overdose conducted over a period of 5 years from 1 January 2004 to 31 December 2008. Patients were divided into two groups: LS group patients had a long hospital stay (> median hours stay in hospital) and SS group patients had a short hospital stay (≤ median hours stay in hospital). Variables were abstracted from medical records for comparison between the two groups. A total of 20 variables were identified for comparison. Parametric and non-parametric tests were used to test differences between groups depending on the normality of the data. SPSS 15 was used for data analysis. Of the 305 patients, 11 factors were identified in the univariate ...Continue Reading

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Jan 15, 2010·Human & Experimental Toxicology·Sa'ed H ZyoudSamah W Al-Jabi

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Citations

May 20, 2015·Regulatory Toxicology and Pharmacology : RTP·Hoi Y TongElena Ramírez
Oct 21, 2016·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Michael S ToceKatherine A O'Donnell

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