Abstract
Transfusion support in haematopoietic stem cell transplantation (HSCT) can be very demanding and challenging. The conditioning regimen, stem cell dose, donor type, presence of GvHD, infection all influence transfusion therapy in haematopoietic stem cell transplantation (HSCT). We retrospectively analysed the first 100 days transfusion requirements among HSCT recipients with haematological as well as non-haematological malignancies in our centre. Transfusion data were retrieved for 100 patients who had undergone HSCT over a period of two years. The HSCT recipients were divided into three groups: autologous, allogenic and haplo-identical. Allogenic group was subdivided into matched related donor (MRD) and matched unrelated donor (MUD). The allo and haplo groups were then classified on the basis of the ABO compatibility as major, minor, bi-directional and compatible. We analysed the mean requirement of blood components (RBC, RDP, SDP and FFP) within the first 100 days of HSCT in each category. Haematologic malignancies constituted 97% of the indications for HSCT. Allo-HSCT constituted 50% of the HSCT, of which 92% were MRD. Auto and haplo-HSCT constituted 40% and 10% respectively. Mean requirement for all products--RBC, SDP, RDP a...Continue Reading
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Citations
Nov 5, 2016·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Rahul NaithaniManoj Singh
Oct 27, 2018·Transfusion·Linda M GriffithDavid F Stroncek
Jun 10, 2019·European Journal of Haematology·Pilar SolvesGuillermo Francisco Sanz
Oct 11, 2019·Transfusion·Shan YuanShirong Wang
Jan 26, 2021·Blood Cells, Molecules & Diseases·José Carlos Jaime-PérezDavid Gómez-Almaguer
Apr 27, 2021·Transfusion·Sitalakshmi SubramanianDaniel Weisdorf