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An analytical model for genetic hitchhiking in the evolution of antimalarial drug resistance

Theoretical Population Biology

Jul 6, 2010

Kristan A Schneider, Yuseob Kim

Abstract

We analytically study a deterministic model for the spread of drug resistance among human malaria parasites. The model incorporates all major characteristics of the complex malaria transmission cycle and accounts for the fact that only a fraction alpha of infected hosts receive drug tre...read more

Mentioned in this Paper

Metabolic Process, Cellular
Short Tandem Repeat
Merozoites
Gametocyte form of protozoa
Coinfection
Recombination, Genetic
Sample Fixation
Hepatic
Acquired Immunity [PE]
Malaria, Falciparum
Paper Details
References
  • References31
  • Citations13
1234
  • References31
  • Citations13
12

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An analytical model for genetic hitchhiking in the evolution of antimalarial drug resistance

Theoretical Population Biology

Jul 6, 2010

Kristan A Schneider, Yuseob Kim

PMID: 20600206

DOI: 10.1016/j.tpb.2010.06.005

Abstract

We analytically study a deterministic model for the spread of drug resistance among human malaria parasites. The model incorporates all major characteristics of the complex malaria transmission cycle and accounts for the fact that only a fraction alpha of infected hosts receive drug tre...read more

Mentioned in this Paper

Metabolic Process, Cellular
Short Tandem Repeat
Merozoites
Gametocyte form of protozoa
Coinfection
Recombination, Genetic
Sample Fixation
Hepatic
Acquired Immunity [PE]
Malaria, Falciparum

Feeds With Similar Papers

Plasmodium Falciparum

Malaria remains a major cause of morbidity and mortality in the tropics, with the parasite Plasmodium falciparum responsible for the majority of the disease burden. Discover the latest research on Plasmodium falciparum.

Malaria Vaccines (ASM)

Research for development of a malaria vaccine is currently underway to find an effective modality to control and eliminate the transmission of malaria. To date, no vaccine has been found to be efficacious in fighting against malaria. Here is the latest research on malaria vaccines.

Related Papers

Paper Details
References
  • References31
  • Citations13
1234
  • References31
  • Citations13
12

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