An ancient plant for the synthesis of a novel carbon dot and its applications as an antibacterial agent and probe for sensing of an anti-cancer drug

Materials Science & Engineering. C, Materials for Biological Applications
M ShahshahanipourZahra Etemadifar

Abstract

An innovative, facile, low- cost and one-pot hydrothermal synthesis was developed for preparing a high fluorescence carbon dots (CDs). In this report for the first time, Lawsonia inermis (Henna) plant as a carbon source was used to produce CDs without adding any chemical reagent and it was characterized by different techniques. The as-synthesized CDs exhibit high stability under various conditions and exceptionally solubility in hydrophilic solvents such as water and ethanol. In addition, the CDs were employed as a biocompatible probe for determination of methotrexate (MTX) in the range of 0.02 μmol L-1 to 18 μmol L-1 with a detection limit as 7 nmol L-1. Highly selective and sensitive determination of MTX was carried out through the fluorescence resonance energy transfer (FRET) mechanism. It is noteworthy that, the antibacterial studies of this CDs lead to interesting results which suggested Henna CDs kill Gram-positive and Gram-negative bacteria like an antibiotic drug. Also, compared with the henna plant, CDs show antibacterial properties in much lower concentrations.

Citations

Sep 11, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Taili ShaoKaoshan Chen
Jun 21, 2020·Biosensors·Muhammad ZulfajriGenin Gary Huang
Aug 15, 2020·Expert Review of Anti-infective Therapy·Mehran AlaviEsmaiel Jabbari
Sep 16, 2020·Materials·Rachael Knoblauch, Chris D Geddes
Feb 6, 2021·Nanomaterials·Arumugam SaravananAharon Gedanken
Mar 5, 2021·Nanomedicine·Gaurav Gopal NaikAlakh N Sahu
May 14, 2021·Luminescence : the Journal of Biological and Chemical Luminescence·Nurul Amalia HumaeraDahlang Tahir
Aug 28, 2021·Nanomaterials·Mattia GhirardelloM Carmen Galan

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