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An ancient satellite repeat controls gene expression and embryonic development in Aedes aegypti through a highly conserved piRNA

bioRxiv

Jan 15, 2020

Rebecca HalbachRonald P. van Rij

Abstract

Tandem repeat elements such as the highly diverse class of satellite repeats occupy large parts of eukaryotic chromosomes. Most occur at (peri)centromeric and (sub)telomeric regions and have been implicated in chromosome organization, stabilization, and segregation. Others are located m...read more

Mentioned in this Paper

Zygote Formation
Heterochromatin-specific nonhistone chromosomal protein HP-1
Transcription, Genetic
Centromere
Finding
Genetic Loci
Protein Expression
Culicidae
Embryo
Mycobacterial Interspersed Repetitive Unit Typing
21
Paper Details
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An ancient satellite repeat controls gene expression and embryonic development in Aedes aegypti through a highly conserved piRNA

bioRxiv

Jan 15, 2020

Rebecca HalbachRonald P. van Rij

DOI: 10.1101/2020.01.15.907428

Abstract

Tandem repeat elements such as the highly diverse class of satellite repeats occupy large parts of eukaryotic chromosomes. Most occur at (peri)centromeric and (sub)telomeric regions and have been implicated in chromosome organization, stabilization, and segregation. Others are located m...read more

Mentioned in this Paper

Zygote Formation
Heterochromatin-specific nonhistone chromosomal protein HP-1
Transcription, Genetic
Centromere
Finding
Genetic Loci
Protein Expression
Culicidae
Embryo
Mycobacterial Interspersed Repetitive Unit Typing
21

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RNA Interference (RNAi) pathway is involved in post-transcriptional gene silencing, transcriptional silencing and epigenetic silencing as well as its use as a tool for forward genetics and therapeutics. Discover the latest preprints on RNAi here.

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Centromere identity must be maintained through multiple generations. A new study reveals a Constitutive Centromere-Associated Network (CCAN)-dependent retention of CENP-A, a key epigenetic mark for centromeres, in centromeres during DNA replication and a replication-dependent error correction to eliminate ectopic CENP-A in chromosome arms. Discover the latest research on centromere in DNA replication here.

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