An anesthesiological approach to nerve agent victims

Military Medicine
Ahmet Cosar, Levent Kenar

Abstract

The potential use of weapons of mass destruction has recently become a real threat even in the areas of ongoing armed conflicts. Mass casualty victims can suffer from psychological and physical trauma. The exposure of physically injured patients to a toxic substance, in a scenario of mass injury, has recently gained major attention among planners of future protocols for emergency medical services. Because rapid deterioration and multiorgan involvement are to be expected after physical injuries, proper organization and complex but efficient acute medical care systems must be organized and deployed to ensure a maximal number of saved lives. These victims will inevitably require urgent surgical intervention and prolonged perioperative care. Understanding the interdependence between the toxic and traumatic occurrences and the drugs used to prevent or treat nerve agent intoxication (pyridostigmine bromide, a reversible inhibitor of acetylcholinesterase; atropine, a muscarinic receptor antagonist that is one of the on-site, first aid, pharmacological resuscitation drugs; and oxime-like pralidoxime chloride or obidoxime chloride, acetylcholinesterase reactivators) is vital. In addition, the administration of anesthesia and emergency s...Continue Reading

Citations

Oct 12, 2018·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Katharina MarquartTimo Wille
May 26, 2007·Anesthesiology·Christian GrasshoffBernd Antkowiak
Aug 3, 2017·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Keith Candiotti
Jan 1, 2017·Current Pulmonology Reports·Nikhil A HuprikarAndrew J Skabelund
Aug 25, 2020·Current Anesthesiology Reports·Christopher M Lam, Michael James Murray
Aug 11, 2010·Toxicology Letters·Berthold DrexlerChristian Grasshoff

❮ Previous
Next ❯

Related Concepts

Related Feeds

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.

Related Papers

European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine
R Ben Abraham, A A Weinbroum
The Journal of the Oklahoma State Medical Association
Ronald A GreenfieldRhett Jackson
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række
Pål Aas, Dag Jacobsen
© 2021 Meta ULC. All rights reserved