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An animal model for assessing pain-on-injection of antibiotics

Journal of Pharmacological Methods

Dec 1, 1980

E CelozziAyelet L Miller

PMID: 7206736

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Abstract

The paw-licking response of rats to a subplantar injection of an antibiotic was used as an indicator of the pain caused by that antibiotic. Good agreement with clinical findings was obtained with cefoxitin, cephalothin, cephradine, cefazolin, cephaloridine, and carbenicillin. Incorporat...read more

Mentioned in this Paper

Local Anesthetics
Antibiotic throat preparations
Cefazolin
Local Anesthetic [EPC]
Antibiotics, ophthalmologic
Antifungal Antibiotics, Topical
Intramuscular Injection
Metazoa
Bacteriocidal Agents
Cephaloridine
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An animal model for assessing pain-on-injection of antibiotics

Journal of Pharmacological Methods

Dec 1, 1980

E CelozziAyelet L Miller

PMID: 7206736

DOI:

Abstract

The paw-licking response of rats to a subplantar injection of an antibiotic was used as an indicator of the pain caused by that antibiotic. Good agreement with clinical findings was obtained with cefoxitin, cephalothin, cephradine, cefazolin, cephaloridine, and carbenicillin. Incorporat...read more

Mentioned in this Paper

Local Anesthetics
Antibiotic throat preparations
Cefazolin
Local Anesthetic [EPC]
Antibiotics, ophthalmologic

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