An Anterior Cruciate Ligament In Vitro Rupture Model Based on Clinical Imaging.

The American Journal of Sports Medicine
Lukas WillingerAndrew A Amis

Abstract

Biomechanical studies on anterior cruciate ligament (ACL) injuries and reconstructions are based on ACL transection instead of realistic injury trauma. To replicate an ACL injury in vitro and compare the laxity that occurs with that after an isolated ACL transection injury before and after ACL reconstruction. Controlled laboratory study. Nine paired knees were ACL injured or ACL transected. For ACL injury, knees were mounted in a rig that imposed tibial anterior translation at 1000 mm/min to rupture the ACL at 22.5° of flexion, 5° of internal rotation, and 710 N of joint compressive force, replicating data published on clinical bone bruise locations. In contralateral knees, the ACL was transected arthroscopically at midsubstance. Both groups had ACL reconstruction with bone-patellar tendon-bone graft. Native, ACL-deficient, and reconstructed knee laxities were measured in a kinematics rig from 0° to 100° of flexion with optical tracking: anterior tibial translation (ATT), internal rotation (IR), anterolateral (ATT + IR), and pivot shift (IR + valgus). The ACL ruptured at 26 ± 5 mm of ATT and 1550 ± 620 N of force (mean ± SD) with an audible spring-back tibiofemoral impact with 5o of valgus. ACL injury and transection increased ...Continue Reading

References

Sep 1, 1993·The Journal of Bone and Joint Surgery. British Volume·A A Amis, B E Scammell
Jan 1, 1993·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·M I Danto, S L Woo
Feb 24, 2004·The American Journal of Sports Medicine·Gene DeMoratWilliam Garrett
Nov 10, 2006·The American Journal of Sports Medicine·Tron KrosshaugRoald Bahr
Jan 2, 2007·Clinical Orthopaedics and Related Research·Denny T T LieAndrew A Amis
Nov 15, 2008·Journal of Biomechanics·Eric G Meyer, Roger C Haut
Dec 3, 2008·The Journal of Bone and Joint Surgery. American Volume·Javad HashemiEugene Dabezies
Feb 3, 2009·The American Journal of Sports Medicine·Barry P BodenTimothy E Hewett
Jun 10, 2010·The American Journal of Sports Medicine·Volker MusahlAndrew D Pearle
Dec 29, 2011·The Journal of Bone and Joint Surgery. American Volume·Kyoung Ho YoonKang-Il Kim
Jul 17, 2012·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Matthew D DriscollWalter R Lowe
May 23, 2013·The American Journal of Sports Medicine·Mary T GoldsmithCoen A Wijdicks
Mar 29, 2014·The American Journal of Sports Medicine·Jocelyn WittsteinWilliam Garrett
Dec 17, 2014·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Philipp ForkelWolf Petersen
Jan 16, 2015·The American Journal of Sports Medicine·Theodore B ShybutWalter R Lowe
Aug 13, 2015·The American Journal of Sports Medicine·Sophia Y KimLouis E DeFrate
Dec 15, 2015·The American Journal of Sports Medicine·Christoph KittlAndrew A Amis
May 15, 2016·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Guan-Yang SongHua Feng
Dec 29, 2016·The American Journal of Sports Medicine·Eivind InderhaugAndrew A Amis
Apr 7, 2018·Journal of Biomechanics·C HalewoodA A Amis
May 8, 2018·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Dhong Won LeeJin Goo Kim
Aug 11, 2018·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·K K AthwalAndrew A Amis
Oct 13, 2018·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Yuichi HoshinoRyosuke Kuroda
Apr 13, 2019·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Alessandro NavacchiaTimothy E Hewett
Jul 17, 2019·The American Journal of Sports Medicine·Junjie ChenEdward M Wojtys
Jan 26, 2020·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Koen C LagaeAndrew A Amis

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Citations

Sep 11, 2021·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Soya MiuraNorimasa Iwasaki

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