Abstract
Staphylococcus aureus bloodstream infections (SABSI) are a major cause of morbidity and mortality in the United States, and proper management is important to effect cure and prevent metastatic foci of infection. We aimed to utilize our antimicrobial stewardship program (ASP) to improve practices at a large academic hospital system. Our ASP implemented a SABSI educational campaign directed at the hospital medicine, cardiology, and infectious diseases divisions. A stewardship intervention was then begun for all patients with SABSI recommending infectious diseases consultation, transesophageal echocardiography (TEE), source control, and preliminary antibiotic changes. A retrospective review was performed for all SABSI cases 2 years before and after implementation of the SABSI intervention. Two hundred forty-three cases before intervention and 259 after intervention were included. An increase in obtaining follow-up negative blood cultures (79.8% vs. 89.6%), infectious diseases consultation (52.7% vs. 86.5%), TEE (25.5% vs. 54.8%), beta-lactam switch for methicillin-susceptible S. aureus (55.2% vs. 74.4%), and source control (41.2% vs. 57.9%) was demonstrated. We demonstrated similar durations of bacteremia, length of stay, relapse,...Continue Reading
References
Mar 21, 1991·The New England Journal of Medicine·W G DanielP R Lichtlen
Oct 8, 1997·Journal of the American College of Cardiology·V G FowlerT Ryan
Oct 14, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·V G FowlerG R Corey
Oct 19, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C GonzálezJ J Picazo
May 18, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S De CastroN G Pandian
Jan 7, 2003·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Harmony R ReynoldsItzhak Kronzon
Sep 25, 2003·Archives of Internal Medicine·Vance G FowlerEugene Z Oddone
Oct 8, 2003·Medicine·Feng-Yee ChangVictor L Yu
Dec 19, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Martin E StryjewskiVance G Fowler
Jan 11, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Catherine LiuHenry F Chambers
Aug 10, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Luis E López-CortésUNKNOWN REIPI/SAB group
May 23, 2014·The Journal of Infection·F TissotL Senn
Feb 24, 2015·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anthony D BaiAndrew M Morris
Sep 17, 2015·Circulation·Larry M BaddourUNKNOWN American Heart Association Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular
Oct 11, 2015·The Journal of Infection·Monique VogelFrank M Brunkhorst
Sep 6, 2017·JAMA Internal Medicine·Michihiko GotoMichael E Ohl
Apr 20, 2018·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Maud B P A AriaansElisabeth H Gisolf