PMID: 9537358Apr 16, 1998Paper

An archaeal aerotaxis transducer combines subunit I core structures of eukaryotic cytochrome c oxidase and eubacterial methyl-accepting chemotaxis proteins

Journal of Bacteriology
A BroounM Alam

Abstract

Signal transduction in the archaeon Halobacterium salinarum is mediated by three distinct subfamilies of transducer proteins. Here we report the complete htrVIII gene sequence and present analysis of the encoded primary structure and its functional features. HtrVIII is a 642-amino-acid protein and belongs to halobacterial transducer subfamily B. At the N terminus, the protein contains six transmembrane segments that exhibit homology to the heme-binding sites of the eukaryotic cytochrome c oxidase. The C-terminal domain has high homology with the eubacterial methyl-accepting chemotaxis protein. The HtrVIII protein mediates aerotaxis: a strain with a deletion of the htrVIII gene loses aerotaxis, while an overproducing strain exhibits stronger aerotaxis. We also demonstrate that HtrVIII is a methyl-accepting protein and demethylates during the aerotaxis response.

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Citations

Jun 10, 2004·Microbiology and Molecular Biology Reviews : MMBR·Hendrik Szurmant, George W Ordal
Mar 9, 2005·Molecular Microbiology·Matthias K Koch, Dieter Oesterhelt
Oct 5, 2010·Archaea : an International Microbiological Journal·Toshio Iwasaki
Feb 15, 2000·Molecular Microbiology·M V Kokoeva, D Oesterhelt
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Sep 25, 2002·Journal of Bacteriology·Simona RomagnoliJudith P Armitage
Apr 23, 2010·Archives of Microbiology·Tobias Schweinitzer, Christine Josenhans
May 25, 2011·Environmental Microbiology·Jesús LacalJuan L Ramos
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Jul 23, 2003·Molecular & Cellular Proteomics : MCP·Young Ah GooWailap V Ng
May 15, 2013·PloS One·Mónica V OrellanaNitin S Baliga
Nov 5, 1999·Annual Review of Microbiology·B L TaylorM S Johnson
Dec 14, 2018·Emerging Topics in Life Sciences·Tessa E F QuaxFriedhelm Pfeiffer
Apr 15, 2017·Cellular and Molecular Life Sciences : CMLS·Abu Iftiaf Md Salah Ud-Din, Anna Roujeinikova
Jun 5, 1999·Microbiology and Molecular Biology Reviews : MMBR·B L Taylor, I B Zhulin

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