An Artificial Neural Network Model for Predicting Successful Extubation in Intensive Care Units

Journal of Clinical Medicine
Meng-Hsuen HsiehChih-Cheng Lai

Abstract

Successful weaning from mechanical ventilation is important for patients in intensive care units (ICUs). The aim was to construct neural networks to predict successful extubation in ventilated patients in ICUs. Data from 1/12/2009 through 31/12/2011 of 3602 patients with planned extubation in Chi-Mei Medical Center's ICUs was used to train and test an artificial neural network (ANN). The input was 37 clinical risk factors, and the output was a failed extubation prediction. One hundred eighty-five patients (5.1%) had a failed extubation. Multivariate analyses revealed that failure was positively associated with therapeutic intervention scoring system (TISS) scores (odds ratio [OR]: 1.814; 95% Confidence Interval [CI]: 1.283⁻2.563), chronic hemodialysis (OR: 12.264; 95% CI: 8.556⁻17.580), rapid shallow breathing (RSI) (OR: 2.003; 95% CI: 1.378⁻2.910), and pre-extubation heart rate (OR: 1.705; 95% CI: 1.173⁻2.480), but negatively associated with pre-extubation PaO₂/FiO₂ (OR: 0.529; 95%: 0.370⁻0.750) and maximum expiratory pressure (MEP) (OR: 0.610; 95% CI: 0.413⁻0.899). A multilayer perceptron ANN model with 19 neurons in a hidden layer was developed. The overall performance of this model was F₁: 0.867, precision: 0.939, and recal...Continue Reading

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Citations

Oct 5, 2019·Journal of Clinical Medicine·Kyoung Hwa LeeYoung Goo Song
Feb 13, 2020·Pulmonary Therapy·Eric MlodzinskiLeo A Celi
Jun 27, 2019·Intensive Care Medicine·Zhong-Hua ShiLeo Heunks
Feb 8, 2020·Critical Care : the Official Journal of the Critical Care Forum·Min Woo KangSeung Seok Han
Oct 20, 2019·Journal of Clinical Medicine·Tsung-Lun TsaiWu-Wei Lai
Nov 5, 2020·Journal of the American College of Emergency Physicians Open·Ikechukwu OhuJestin N Carlson
Apr 4, 2021·International Journal of Environmental Research and Public Health·Ying-Jen ChangChung-Feng Liu
Jun 3, 2021·Journal of Clinical Medicine·Jong Ho KimMoon Seong Baek
Aug 8, 2021·BMC Medical Informatics and Decision Making·Yan LuoCong Wang
Feb 3, 2022·British Medical Bulletin·Andrew BisharaMervyn Maze

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Methods Mentioned

BETA
PCA
sedation

Software Mentioned

Statistica
Adam
learn
scikit
Python
SPSS
Tensorflow

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