An assessment of evidence data gaps in the investigation of possible transmission routes of extended spectrum β-lactamase producing Escherichia coli from livestock to humans in the UK

Preventive Veterinary Medicine
V HoriganR R L Simons

Abstract

Antimicrobial resistance (AMR) threatens the effective prevention and treatment of bacterial diseases in both humans and animals. Globally, there has been much research done regarding resistant bacteria in the livestock industry, but few published resources collate this information. This report discusses a risk assessment (RA) framework and subsequent analysis of data availability for AMR in bacteria from 4 livestock sectors: dairy cattle, beef cattle, pigs and poultry, with particular reference to ESBL-producing Escherichia coli (ESBL E. coli) prevalence in the dairy cattle sector within the United Kingdom. The aim of this assessment was to identify where quality data exist, for the purpose of parameterising a quantitative RA, and where it would be useful to direct future research to provide quality data to improve the current knowledge base. Such research is necessary to support risk modelling and forecasting capability regarding the relative contributions of factors that maintain the emergence and spread of AMR in bacteria. The review suggested that there are data gaps regarding ESBL E. coli occurrence in the following: beef cattle, bulk tank milk and dairy products, animal-by-products, the farm environment (including after ...Continue Reading

References

Apr 23, 2004·The Journal of Antimicrobial Chemotherapy·Emma L SnaryMarion Wooldridge
May 14, 2004·The Journal of Antimicrobial Chemotherapy·Beth E Karp, Jørgen Engberg
Sep 17, 2008·Risk Analysis : an Official Publication of the Society for Risk Analysis·Louis Anthony Tony Cox, Douglas A Popken
Nov 6, 2008·Animal Health Research Reviews·Douglas R CallAshish A Sawant
Apr 6, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M A Leverstein-van HallUNKNOWN National ESBL surveillance group
Jun 20, 2014·Current Opinion in Microbiology·Randall S Singer, Jessica Williams-Nguyen

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Citations

Jan 24, 2018·Frontiers in Veterinary Science·Chetan SharmaHarsh Panwar
Dec 22, 2017·The Veterinary Record·Robert M HydeMartin J Green
Nov 18, 2017·Veterinary Sciences·Muhammad Attiq RehmanMoussa Sory Diarra
Feb 27, 2018·EFSA Journal·UNKNOWN European Food Safety Authority, UNKNOWN European Centre for Disease Prevention and Control
Jul 31, 2020·Journal of Food Protection·John W SchmidtTommy L Wheeler

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