An Assessment of Radiation-Associated Risks of Mortality from Circulatory Disease in the Cohorts of Mayak and Sellafield Nuclear Workers

Radiation Research
T V AzizovaR M Agius

Abstract

Mortality from circulatory disease (CD), ischemic heart disease (IHD) and cerebrovascular disease (CeVD) was investigated in relationship to cumulative doses of external gamma radiation and internal alpha radiation to the liver from deposited plutonium over long follow-up periods in two large cohorts of nuclear workers: the Russian Mayak Worker Cohort (MWC) and the UK Sellafield Worker Cohort (SWC). The MWC comprised 22,374 workers (74.6% males) with 5,123 CD deaths registered during 842,538 person-years of follow-up, while the SWC comprised 23,443 workers (87.8% males) with 2,322 CD deaths registered during 602,311 person-years of follow-up. Dose estimates for external gamma radiation and internal alpha radiation to the liver were calculated via a common methodology, in accordance with an agreed protocol. The mean cumulative external Hp(10) dose was 0.52 Sv for the MWC and 0.07 Sv for the SWC, while the mean cumulative internal dose was 0.19 Gy for the MWC and 0.01 Gy for the SWC. Categorical relative risks (RR) and excess relative risks (ERR) per unit dose were estimated for each cohort and for the pooled cohort when appropriate. The dose responses for CD, IHD and CeVD in relationship to internal alpha-particle dose did not d...Continue Reading

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Citations

Mar 13, 2019·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Wei ZhangNezahat Hunter
May 2, 2019·Bioscience Reports·Yezhou LiuJinhai Jia
Aug 16, 2018·British Journal of Cancer·Richard Wakeford
Sep 29, 2018·Dose-response : a Publication of International Hormesis Society·Alexander VaisermanYehoshua Socol
May 22, 2019·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Anthony RiddellFrank de Vocht
Dec 13, 2019·Dose-response : a Publication of International Hormesis Society·Lingong JiangShuyu Zhang
Sep 5, 2020·Occupational and Environmental Medicine·Jeri L AndersonRobert Douglas Daniels
Nov 7, 2020·Environment International·Soile TapioSisko Salomaa
Dec 15, 2020·Frontiers in Psychiatry·Konstantyn N LoganovskyYuliya S Voychulene
May 29, 2021·International Journal of Radiation Biology·John D BoiceRichard W Leggett
Jun 24, 2021·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Richard Wakeford
Sep 16, 2021·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·Colin J Martin, Michael Barnard
Dec 9, 2021·Annals of the ICRP·M TirmarcheS Zhivin

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