An assessment of the ability of a silver-releasing device to prevent bacterial contamination of urethral catheter drainage systems

British Journal of Urology
D SticklerT J Williams

Abstract

To investigate the ability of a silver-releasing device to protect the catheterized bladder from infection by blocking the ascending migration of bacteria from contaminated urine-drainage bags. A simple physical model of the catheterized bladder and drainage system was used with the device located in the drainage-tube just below the sampling port. Urine was supplied to the model at 1.0 mL/min and the drainage bag was contaminated with Pseudomonas aeruginosa, Escherichia coli and Proteus mirabilis. Over 10 days, urine from the bag, catheter sampling-port and bladder were examined for contamination. Bacteriological analysis showed that the mean time for test organisms to reach the sampling ports of four different control bag systems ranged from 5.7 to 7.7 days. Urine from the sampling ports of the test systems incorporating the silver device remained sterile for 10 days. The device also prevented the growth of the large populations of bacteria (10(8) colony-forming units per mL) that occurred in the control bags. While scanning electron microscopy showed the formation of bacterial biofilm throughout the control drainage systems, no bacterial colonization was visible on the surfaces of the test systems. Chemical analysis establish...Continue Reading

Citations

Dec 23, 2004·Urological Research·Greg L ShawChristopher Fry
Mar 24, 2004·International Journal of Antimicrobial Agents·Peter TenkeElisabeth Nagy
Apr 11, 2001·International Journal of Antimicrobial Agents·G ReidM Beheshti
Feb 29, 2008·Journal of Biomedical Materials Research. Part a·Samuel D Conzone, Delbert E Day
Jan 22, 2010·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Brendan F GilmoreSean P Gorman
Sep 14, 2001·Emergency Medicine Clinics of North America·H Blumstein
Jul 2, 2005·Medical Engineering & Physics·E L Lawrence, I G Turner
Oct 2, 2009·FEMS Immunology and Medical Microbiology·Astha AgarwalAmita Jain
May 25, 2018·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Cathy Murphy
Apr 6, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Shu-Hua YangKo-Shau Chen
Oct 19, 2012·The Cochrane Database of Systematic Reviews·Patrick JahnGero Langer
Sep 11, 2019·Journal of Applied Microbiology·M AyyashA G Al-Bakri
Mar 16, 2007·Expert Review of Medical Devices·Turlough M HamillSean P Gorman
Jan 1, 2004·JBI Library of Systematic Reviews·Craig LockwoodZuben Florence

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.