Abstract
Dyslipidemia in patients with glycogen storage disease types Ia (GSD Ia) and III (GSD III) does not lead to premature atherosclerosis. The aim of this study was to investigate the association among serum copper (Cu), zinc (Zn), iron (Fe), and selenium (Se) concentrations, and their carrier proteins: ceruloplasmin, albumin, and related antioxidant enzyme activities [superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), paraoxonase (PON), and arylesterase (ARYL)] in 20 GSD Ia and 14 III patients compared to age and sex matched 20 healthy subjects. Erythrocyte oxidative stress was measured by erythrocyte thiobarbituric acid reactive substances (eTBARSs). Hypertriglyceridemia [333 (36-890)mg/dL] in GSD Ia and hypercholesterolemia with elevated LDL-cholesterol [188 (91-313)mg/dL] and decreased HDL-cholesterol [32(23-58)mg/dL] levels in GSD III were found. Serum Cu, Fe, and Zn showed no significant differences between groups. However, Se 60 (54-94), 81 (57-127) microg/L, ceruloplasmin 21 (10-90), 27 (23-65) microg/L, and albumin 2.4 (1.7-5.1), 2.8 (1.8-4.06)g/dL levels were decreased in GSD Ia and III groups, respectively, in comparison with the controls [Se 110 (60-136) microg/L, ceruloplasmin 72 (32-94) microg/L...Continue Reading
References
Jul 27, 1992·FEBS Letters·B Halliwell, J M Gutteridge
Nov 1, 1995·Free Radical Research·P J EvansB Halliwell
Sep 30, 1994·Atherosclerosis·P J LeeJ V Leonard
Feb 1, 1994·Annals of Internal Medicine·G M TalenteJ I Wolfsdorf
Jun 1, 1993·Circulation·W H GilesJ Marks
Jul 27, 1999·Archives of Internal Medicine·B de Valk, J J Marx
Jul 25, 2000·American Journal of Epidemiology·E S Ford
Jun 28, 2002·Free Radical Biology & Medicine·Birgit WittensteinAlfried Kohlschütter
Apr 9, 2004·Lancet·Albert WiegmanJohn J P Kastelein
Jun 17, 2006·Molecular Genetics and Metabolism·Andrew D NguyenJanice Y Chou
Apr 5, 2007·Journal of Inherited Metabolic Disease·T GeberhiwotR Cramb
Sep 11, 2008·Current Medicinal Chemistry·Xi-Ming Yuan, Wei Li
Dec 17, 2008·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·S Kalkan UcarS Darcan
Citations
Nov 6, 2010·Molecular Biology Reports·Yan-Bo LiJing Wang
Feb 8, 2013·Biological Trace Element Research·Guanghuan WangXuezhi Shi
Dec 22, 2015·Biological Trace Element Research·Fereshteh BahmaniAhmad Esmaillzadeh
Aug 8, 2015·Nutrition·Zatollah AsemiAhmad Esmaillzadeh
May 2, 2014·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Camila PuglieseFernanda Luisa Ceragioli Oliveira
Jan 13, 2015·Biological Trace Element Research·Guangtao XuJiang Gu
Dec 5, 2014·Biological Trace Element Research·Guanghuan WangXueyong Feng
May 24, 2013·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Asmaa M ZahranMona A H El-Baz
Feb 15, 2018·Oxidative Medicine and Cellular Longevity·Ning WangYibin Feng
Feb 20, 2018·BioMed Research International·Ling-Jun WangLu Lu
Nov 30, 2018·International Journal of Environmental Research and Public Health·Susana Rivera-MancíaJosé Pedraza-Chaverri
Feb 14, 2019·Lipids in Health and Disease·Yanna ZhuYajun Chen
Jun 3, 2021·Nutrients·Shinya NakataniMasanori Emoto
Oct 22, 2021·Biological Trace Element Research·Bing CaoNan Li