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An atomic model of brome mosaic virus using direct electron detection and real-space optimization

Nature Communications

Sep 4, 2014

Zhao Hui WangWah Chiu

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Abstract

Advances in electron cryo-microscopy have enabled structure determination of macromolecules at near-atomic resolution. However, structure determination, even using de novo methods, remains susceptible to model bias and overfitting. Here we describe a complete workflow for data acquisiti...read more

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  • An atomic model of brome mosaic virus using direct electron detection and real-space optimization

    Nature Communications

    Sep 4, 2014

    Zhao Hui WangWah Chiu

    PMID: 25185801

    DOI: 10.1038/ncomms5808

    Abstract

    Advances in electron cryo-microscopy have enabled structure determination of macromolecules at near-atomic resolution. However, structure determination, even using de novo methods, remains susceptible to model bias and overfitting. Here we describe a complete workflow for data acquisiti...read more

    1
    79

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