PMID: 8972048Oct 1, 1996Paper

An attenuated bovine herpesvirus 1 marker vaccine induces a better protection than two inactivated marker vaccines

Veterinary Microbiology
J C BoschJ T van Oirschot

Abstract

A comparative study on the efficacy of 3 bovine herpesvirus 1 (BHV1) marker vaccines was carried out. An attenuated gE-negative vaccine, an inactivated gE-negative vaccine and an experimental gD-subunit vaccine were tested twice in a vaccination-challenge experiment in cattle. The attenuated vaccine induced the best clinical protection as evidenced by the total absence of clinical signs and fever in cattle. In addition, the attenuated vaccine reduced the shedding of challenge virus significantly more than the inactivated vaccines. Of the inactivated vaccines, the gE-negative vaccine induced a better clinical protection than the gD-subunit vaccine.

Citations

Feb 8, 2002·Comparative Immunology, Microbiology and Infectious Diseases·G CastrucciR Angelini
Mar 23, 2000·Preventive Veterinary Medicine·A V NoordegraafA A Dijkhuizen
Sep 16, 1999·Journal of Biotechnology·J T van Oirschot
Aug 5, 2000·Veterinary Microbiology·M H MarsJ T van Oirschot
Jul 22, 2011·Research in Veterinary Science·T GeraghtyL O'Grady
Jul 14, 2010·The Veterinary Clinics of North America. Food Animal Practice·Gerald L Stokka
Oct 1, 2015·The Veterinary Record·J M E StathamS C Archer
Jul 4, 2015·The Veterinary Clinics of North America. Food Animal Practice·Gerald Stokka, Timothy J Goldsmith
Jun 24, 2014·The Veterinary Journal·Kerli RaaperiArvo Viltrop
Dec 7, 2005·Veterinary Microbiology·Sylvia van Drunen Littel-van den Hurk
Dec 13, 2005·Veterinary Microbiology·Mathias Ackermann, Monika Engels
Jan 30, 2007·Veterinary Research·Benoît MuylkensEtienne Thiry
Apr 9, 1998·The Veterinary Record·G J WellenbergJ T van Oirschot
Sep 8, 2021·Frontiers in Veterinary Science·I M G A Santman-BerendsG van Schaik

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