PMID: 8597970Jan 1, 1995Paper

An audit of adverse events in children sedated with chloral hydrate or propofol during imaging studies

Paediatric Anaesthesia
C MerolaS M Barst

Abstract

We examined records of sedations provided by the paediatric anaesthesiology staff for 455 children (ages 1 mo-17 yr) undergoing MRI or CT scans at our institution over a twelve-month period with regard to the monitoring of adverse events: excessive sedation, agitation, vomiting, hypoxaemia, and major airway compromise. One hundred-and-thirty-one patients (29%) received chloral hydrate; 324 patients (71%) received propofol. All patients were monitored with continuous noninvasive pulse oximetry and received supplemental oxygen via nasal cannulae. Of the patients who received chloral hydrate, 64 (49%) were over one year of age; of the patients who received propofol, 318 (98%) were one year of age or older. In the chloral hydrate group, 23 patients (19%) were deemed excessively sedated and four patients (3%) were agitated; no patients in the propofol group experienced any of the adverse outcomes reviewed. Furthermore, no patients in either group had significant airway compromise and none was admitted to the hospital as a result of the sedation.

References

Sep 1, 1992·Anaesthesia·A Gupta, M Vegfors
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Aug 1, 1992·Anaesthesia·M VangervenH Van Aken
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Citations

Jan 17, 2012·Pediatric Radiology·C Heng VongP Marec Bérard
Dec 1, 2006·Journal of Autism and Developmental Disorders·Dennis P CarmodyMichael Lewis
Aug 18, 2012·The British Journal of Radiology·Y Arlachov, R H Ganatra
Mar 30, 2012·The British Journal of Radiology·K O'ReganN Fanning
Feb 18, 2010·Current Problems in Surgery·Avihu Z GazitA Thomas Pezzella
Dec 22, 2007·Paediatric Anaesthesia·Michael R J Sury, Jonathan H Smith
Sep 29, 2004·Journal of Emergency Nursing : JEN : Official Publication of the Emergency Department Nurses Association·Sharon E MaceUNKNOWN EMSC Grant Panel on Pharmacologic Agents Used in Pediatric Sedation and Analgesis in the Emergency Department
Aug 25, 2005·Clinical Therapeutics·K J S AnandGary A Walco
Jun 28, 2005·Clinical Radiology·M R J SuryW K Chong
Nov 12, 2002·Magnetic Resonance Imaging Clinics of North America·Sudha Anupindi, Diego Jaramillo
Sep 9, 2006·Brain Research·Dennis P Carmody, Michael Lewis
Jun 10, 2000·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·M MovagharJ Doyle
Oct 27, 2004·Anesthesia and Analgesia·Joseph P Cravero, George T Blike
Sep 27, 2005·Journal of Neurosurgical Anesthesiology·Laurie B AmundsenGeraldine Dawson
Oct 22, 2005·Mental Retardation and Developmental Disabilities Research Reviews·Senthil K SundaramDiane C Chugani
May 5, 2011·Expert Review of Neurotherapeutics·Ramesh Ramaiah, Sanjay Bhananker
Oct 6, 2006·Current Opinion in Anaesthesiology·Joseph P Cravero, George T Blike
Oct 6, 2020·Journal of Anaesthesiology, Clinical Pharmacology·Aakriti GuptaAnmol Bhatia
Oct 12, 2021·International Journal of Clinical Oncology·Tadashi KumamotoYukiko Tsunematsu

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