An automatic approach for calibrating dielectric bone properties by combining finite-element and optimization software tools

Computer Methods in Biomechanics and Biomedical Engineering
Yukun SuRainer Bader

Abstract

The dielectric properties of human bone are one of the most essential inputs required by electromagnetic stimulation for improved bone regeneration. Measuring the electric properties of bone is a difficult task because of the complexity of the bone structure. Therefore, an automatic approach is presented to calibrate the electric properties of bone. The numerical method consists of three steps: generating input from experimental data, performing the numerical simulation, and calibrating the bone dielectric properties. As an example, the dielectric properties at 20 Hz of a rabbit distal femur were calibrated. The calibration process was considered as an optimization process with the aim of finding the optimum dielectric bone properties that match most of the numerically calculated simulation and experimentally measured data sets. The optimization was carried out automatically by the optimization software tool iSIGHT in combination with the finite-element solver COMSOL Multiphysics. As a result, the optimum conductivity and relative permittivity of the rabbit distal femur at 20 Hz were found to be 0.09615 S/m and 19522 for cortical bone and 0.14913 S/m and 1561507 for cancellous bone, respectively. The proposed method is a potent...Continue Reading

References

Jan 1, 1989·Annals of Biomedical Engineering·S Saha, P A Williams
Mar 1, 1984·Medical & Biological Engineering & Computing·S SahaJ A Albright
Feb 1, 1983·IEEE Transactions on Bio-medical Engineering·J D KosterichS R Pollack
Nov 1, 1996·Physics in Medicine and Biology·C GabrielE Corthout
Jan 26, 1999·Clinical Orthopaedics and Related Research·M W OtterC T Rubin
Mar 17, 2004·Clinical Orthopaedics and Related Research·Roy K AaronBruce J Simon
Feb 24, 2009·Computer Methods and Programs in Biomedicine·Daniel KluessRainer Bader
Jun 30, 2011·IEEE Transactions on Bio-medical Engineering·Brad M IsaacsonRob S MacLeod
Feb 2, 2013·Operative Orthopädie und Traumatologie·M EllenriederW Mittelmeier
Sep 23, 2014·Expert Review of Medical Devices·Marco P Soares dos SantosTatiana Oliveira

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Citations

Mar 20, 2021·Biomechanics and Modeling in Mechanobiology·Yogesh Deepak BansodUrsula van Rienen

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Software Mentioned

CallComsol
DOE
Amira
ABAQUS
Geomagic
COMSOL Multiphysics
COMSOL
iSIGHT
Matlab

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