An efficient soft tissue characterization algorithm from in vivo indentation experiments for medical simulation

The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS
Jung KimM A Srinivasan

Abstract

Realistic virtual reality surgical training simulators require an accurate biomechanical model of in vivo soft tissue behaviour. One of the challenges in modelling is to characterize soft tissue properties incorporating the experimental measurements of organ behaviour. Organ measurements were collected from intra-abdominal organs of pigs, using a robotic indenter and a force transducer. The constitutive model was fitted to the in vivo data using the Levenberg-Marquardt optimization algorithm, combined with a three-dimensional non-linear finite element (FE) simulation. This paper presents an integrated framework for measuring, modelling and calibrating organs' material properties and provides parameters for modelling pigs' intra-abdominal organs. The calibrated mechanical models are suitable for computing accurate reaction forces on surgical instruments and for computing the deformations of organs. They also provide a useful benchmark for measuring the realism of real-time tissue models used in virtual reality-based surgical trainers.

References

Aug 1, 1995·Journal of Biomechanics·M J MoultonM K Pasque
Sep 1, 1993·The American Review of Respiratory Disease·S Q Liu, Y C Fung
May 1, 1996·Journal of Biomechanical Engineering·G A JohnsonK R Rajagopal
Aug 28, 1999·Journal of Biomechanical Engineering·E O CarewI Vesely
Feb 15, 2000·Journal of Biomechanics·K Miller
Aug 15, 2000·Journal of Biomechanics·K MillerP Bednarz
Dec 4, 2001·Medical Image Analysis·F J CarterA Cuschieri
Aug 22, 2003·Journal of Biomechanical Engineering·Padmanabhan Seshaiyer, Jay D Humphrey
Nov 1, 2006·IEEE Transactions on Bio-medical Engineering·Boon K TayMandayam A Srinivasan
Mar 16, 2007·IEEE Transactions on Bio-medical Engineering·Teeranoot ChanthasopeephanAlan C W Lau

❮ Previous
Next ❯

Citations

Nov 7, 2012·Journal of the Mechanical Behavior of Biomedical Materials·Sagar UmaleRemy Willinger
Aug 12, 2015·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Mohammad Reza DehghanMohammad Zareinejad
Apr 13, 2011·Journal of Biomechanics·Sagar UmaleRemy Willinger
May 3, 2013·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Mohammad NikkhooJaw-Lin Wang
May 27, 2020·International Journal for Numerical Methods in Biomedical Engineering·Antonio CanditoYuhang Chen
Jul 10, 2012·Medical & Biological Engineering & Computing·Bummo AhnJung Kim
Jan 4, 2019·Proceedings of the National Academy of Sciences of the United States of America·Raphaël MichelLaurent Corté
Oct 12, 2012·Medical & Biological Engineering & Computing·Stéphane BourgouinStéphane V Berdah

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.