An electrochemical approach of the redox behavior of water insoluble ubiquinones or plastoquinones incorporated in supported phospholipid layers

Biophysical Journal
D MarchalC Bourdillon

Abstract

Physiological mole fractions of long isoprenic chain ubiquinone (UQ[10]) and plastoquinone (PQ9) were incorporated inside a supported bilayer by vesicle fusion. The template of the bilayer was an especially designed microporous electrode that allows the direct electrochemistry of water insoluble molecules in a water environment. The artificial structure, made by self-assembly procedures, consisted of a bilayer laterally in contact with a built-in gold electrode at which direct electron transfers between the redox heads of the quinones molecules and the electrode can proceed. The mass balances of quinone and lipid in the structure were determined by radiolabeling and spectrophotometry. A dimyristoyl phosphatdylcholine stable surface concentration of 250 +/- 50 pmol x cm(-2), unaffected by the presence of the quinone, was measured in the fluid monolayer. The mole fraction of quinone was between 1 and 3 mol%, remaining unchanged when going from the vesicles to the supported layers. The lipid molecules and the quinone pool were both laterally mobile, and cyclic voltammetry was used to investigate the redox properties of UQ10 and PQ9 over a wide pH range. Below pH 12, the two electrons-two protons electrochemical process at the gold...Continue Reading

Citations

Mar 1, 2015·Bioelectrochemistry·Javier HoyoFausto Sanz
Oct 23, 2015·The European Physical Journal. E, Soft Matter·Frédéric HarbBernard Tinland
Jun 29, 2011·Physical Chemistry Chemical Physics : PCCP·Celia LemmerRita Meunier-Prest
May 7, 2020·European Biophysics Journal : EBJ·Karuppasamy DharmarajFritz Scholz
Mar 3, 2012·The Journal of Physical Chemistry. B·Rui Campos, Ritu Kataky
May 10, 2011·Journal of the American Chemical Society·Ivan BogeskiMarkus Hoth
Mar 5, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·C WhitehouseA Nelson

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