An electroconvulsive therapy procedure impairs reconsolidation of episodic memories in humans

Nature Neuroscience
Marijn C W KroesGuillén Fernández

Abstract

Despite accumulating evidence for a reconsolidation process in animals, support in humans, especially for episodic memory, is limited. Using a within-subjects manipulation, we found that a single application of electroconvulsive therapy following memory reactivation in patients with unipolar depression disrupted reactivated, but not non-reactivated, memories for an emotional episode in a time-dependent manner. Our results provide evidence for reconsolidation of emotional episodic memories in humans.

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Citations

Jun 4, 2014·Current Psychiatry Reports·Eric VermettenHarm J Krugers
Jan 23, 2016·Annals of the New York Academy of Sciences·Stephanie A Gagnon, Anthony D Wagner
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