PMID: 109066Dec 1, 1978

An electrophysiological investigation of skeletal muscle in human chronic Chagas' disease

Arquivos de neuro-psiquiatria
O P SanzR E Sica

Abstract

An electrophysiological study has been made of the thenar, hypothenar, soleus and extensor digitorum brevis muscles and their inervation in 90 patients with chronic Chagas' disease. Some of them showed a reduced number of functional motor units with increased size of many of the surviving units. No decremental muscle response was found to repetitive nerve stimulation. Motor and sensory conduction velocities as well as motor terminal latencies were on the normal range. These findings suggested that the muscle changes resulted from a primary defect of the alpha spinal motoneurone soma.

References

Dec 1, 1978·Arquivos de neuro-psiquiatria·M A PaganoR E Sica
Jun 1, 1975·Arquivos de neuro-psiquiatria·R E Sica, O P Sanz
Feb 13, 1971·Lancet·A J McComasM J Campbell
Jan 1, 1974·Journal of Neurology, Neurosurgery, and Psychiatry·R E SicaD Longmire
Aug 1, 1971·Journal of Neurology, Neurosurgery, and Psychiatry·A J McComasA Upton
Dec 1, 1971·Journal of Neurology, Neurosurgery, and Psychiatry·R E SicaA Upton
Apr 1, 1971·Journal of Neurology, Neurosurgery, and Psychiatry·A J McComasR E Sica

Citations

Nov 1, 1987·Journal of the Neurological Sciences·H A MolinaM T Rimoldi
Oct 2, 2003·Trends in Parasitology·R L Tarleton
Dec 1, 1991·Arquivos de neuro-psiquiatria·R E SicaM Gargia Erro
Dec 1, 1978·Arquivos de neuro-psiquiatria·M A PaganoR E Sica
Jun 1, 1996·Arquivos de neuro-psiquiatria·O M GenoveseR E Sica
Sep 1, 1989·Arquivos de neuro-psiquiatria·O M GenoveseR E Sica
Sep 1, 1988·Arquivos de neuro-psiquiatria·C R DeFariaA Rassi
Sep 1, 1990·Arquivos de neuro-psiquiatria·R F Pelli-NobleE Graiff de Riarte

Related Concepts

Electrophysiology (Science)
Motor Endplate
Motor Neurons
Muscle
Nerve Degeneration
Nerve Conduction Function
Perineurium
Chagas Disease

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.