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An empirical evaluation of the common disease-common variant hypothesis

BMC Proceedings

Dec 18, 2007

Gary T ChenJohn S. Witte

PMID: 18466549

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Abstract

While genome-wide linkage studies have been successful in mapping variants underlying rare monogenic disorders, genome-wide association studies may be more appropriate for detecting common variants of modest effects that underlie common disorders. To this end, we were interested in dete...read more

An empirical evaluation of the common disease-common variant hypothesis

BMC Proceedings

Dec 18, 2007

Gary T ChenJohn S. Witte

PMID: 18466549

DOI:

Abstract

While genome-wide linkage studies have been successful in mapping variants underlying rare monogenic disorders, genome-wide association studies may be more appropriate for detecting common variants of modest effects that underlie common disorders. To this end, we were interested in dete...read more

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