An entry to vinylcyclopropane through palladium-catalyzed intramolecular cyclopropanation of alkenes with unstabilized allylic tosylhydrazones

Chemical Communications : Chem Comm
Yang YangSong Qin

Abstract

A diastereoselective Pd-catalyzed intramolecular cyclopropanation of alkenes with unstabilized allylic tosylhydrazones was developed. This methodology provides an efficient entry toward synthesis of the bicyclo[3.1.0] hexane system with an exo-double bond, and sets the basis for future elaboration of more complex polycyclic motifs.

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Citations

Aug 1, 2015·The Journal of Organic Chemistry·Karel Le JeuneHervé Clavier
Sep 15, 2018·Natural Product Reports·Yuye ChenJing Xu
Jan 21, 2020·Chemical Society Reviews·Dong ZhuShifa Zhu
Mar 30, 2017·Chemical Society Reviews·Ying Xia, Jianbo Wang
Sep 14, 2019·Organic Letters·Guili ZhuBo Liu

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