PMID: 175099Jan 1, 1976Paper

An epidemic of diarrhoea in human neonates involving a reovirus-like agent and 'enteropathogenic' serotypes of Escherichia coli

Journal of Clinical Pathology
R F BishopB J Ruck

Abstract

During December 1974, an epidemic of diarrhoea occurred in the Royal Children's Hospital, Melbourne, in a ward caring for neonates with acute or chronic medical and surgical problems. Electron microscopy of diarrhoeal faeces revealed a reovirus-like particle ('duovirus' or 'rotavirus') known to cause acute enteritis in older children. This virus is considered to have been primarily involved in the aetiology of the epidemic. In addition, three 'enteropathogenic' serotypes of Escherichia coli were isolated from babies during the epidemic, but none produced enterotoxin when tested in ligated ileal loops of rabbits or in monolayers of Y1 adrenal cells. Further epidemics of neonatal diarrhoea must be studied using culture and electron microscopy of faeces to determine the relative importance of this virus and of E. coli in the aetiology of diarrhoea in this age-group.

References

Apr 1, 1975·Journal of Clinical Pathology·G P DavidsonB J Ruck
Apr 1, 1966·The Journal of Infectious Diseases·W Burrows, G M Musteikis
Aug 10, 1956·Annals of the New York Academy of Sciences·F S CHEEVER

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Citations

Jan 1, 1978·Archives of Virology·T H Flewett, G N Woode
Jan 15, 1983·British Medical Journal·A R SamadiQ S Ahmed
Aug 1, 1976·Journal of Clinical Pathology·B RoweS M Scotland
Dec 1, 1978·European Journal of Pediatrics·T MorishimaS Suzuki
Jun 1, 1982·The Journal of Hospital Infection·H S Holzel, W D Cubitt
Dec 1, 1984·The Journal of Hospital Infection·F J WaltherM S Daniels-Bosman
Jan 1, 1980·Journal of Medical Virology·L Van RenterghemJ Tilleman
Jan 1, 1982·The Journal of Infection·A S BrydenI Craig
Aug 1, 2014·Frontiers in Microbiology·Fiona J Baird, Andreas L Lopata
Jul 24, 2004·Expert Review of Vaccines·Graeme Barnes
Dec 1, 1978·The Journal of Pediatrics·H C SprattC H Pai
Jun 1, 1990·Journal of Youth and Adolescence·J M Zarb
Jun 1, 1980·Teratology·B J PolandB Paradice
Jan 1, 1988·Immunogenetics·L K GaurE A Clark
Apr 1, 1991·Revista de saúde pública·K E StewienE R Baldacci
Dec 19, 2002·The Pediatric Infectious Disease Journal·Renu SharmaRobert A Hollister
Mar 1, 1985·Journal of Clinical Microbiology·Y HoshinoA Z Kapikian
Jun 3, 1978·Lancet·I L ChrystieJ E Banatvala
Apr 1, 1980·The Journal of Pediatrics·M C Steinhoff
Sep 1, 1983·The Journal of Pediatrics·H A RotbartJ Jantzen

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