An epidemiologic-based survey of public attitudes towards predictive genetic testing in Russia

Personalized Medicine
Oksana A MakeevaValery P Puzyrev

Abstract

Many new genetic tests for common multifactorial disorders are becoming available to individuals, including direct-to-consumer genotyping services. Typically, studies of public attitudes reveal a high level of interest for individual genotyping. In a Russian urban population, 85% of 2000 respondents answered positively to a question about their own willingness to undergo predictive genetic testing for preventable health conditions. Gender, age and health status significantly influenced response. Multivariate discriminant analyses revealed that wanting to know about probable future diseases, readiness to improve lifestyles and an interest in learning about individual genome characteristics are the most important predictors for wanting to be tested. Along with the high level of interest, highly overestimated expectations were encountered in many studies. With the low predictive abilities of currently available genetic tests for common disorders, proper interpretation of the data and genetic counseling are essential. There is a need for prospective validation of genetic panels for risk assessments, and for efforts to measure the effects of genetic information disclosure and how this information might contribute to lifestyle changes.

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Apr 9, 2013·Nutrition Research Reviews·R FallaizeJ A Lovegrove
Oct 25, 2014·The Proceedings of the Nutrition Society·Barbara Stewart-KnoxLynn J Frewer
Mar 18, 2017·Genetic Testing and Molecular Biomarkers·Davit ChokoshviliPascal Borry
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Mar 31, 2021·Journal of Community Genetics·Eka KvaratskheliaElene Abzianidze
Aug 28, 2021·International Journal of Environmental Research and Public Health·Azimatun Noor AizuddinSyed Mohamed Aljunid

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Methods Mentioned

BETA
genotyping
to

Software Mentioned

deCODE

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