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An essential complementary role of NF-kappaB pathway to microbicidal oxidants in Drosophila gut immunity

The EMBO Journal

Jul 22, 2006

Ji-Hwan RyuWon-Jae Lee

Abstract

In the Drosophila gut, reactive oxygen species (ROS)-dependent immunity is critical to host survival. This is in contrast to the NF-kappaB pathway whose physiological function in the microbe-laden epithelia has yet to be convincingly demonstrated despite playing a critical role during s...read more

Mentioned in this Paper

NFKB1 gene
Relish protein, Drosophila
Drosophila
NF-Kappa B p65
Intestines
Biochemical Pathway
Intestinal Wall Tissue
Sepsis
Amphipathic Cationic Antimicrobial Peptides
Failed Back Surgery Syndrome
Paper Details
References
  • References45
  • Citations58
12345...

An essential complementary role of NF-kappaB pathway to microbicidal oxidants in Drosophila gut immunity

The EMBO Journal

Jul 22, 2006

Ji-Hwan RyuWon-Jae Lee

PMID: 16858400

DOI: 10.1038/sj.emboj.7601233

Abstract

In the Drosophila gut, reactive oxygen species (ROS)-dependent immunity is critical to host survival. This is in contrast to the NF-kappaB pathway whose physiological function in the microbe-laden epithelia has yet to be convincingly demonstrated despite playing a critical role during s...read more

Mentioned in this Paper

NFKB1 gene
Relish protein, Drosophila
Drosophila
NF-Kappa B p65
Intestines
Biochemical Pathway
Intestinal Wall Tissue
Sepsis
Amphipathic Cationic Antimicrobial Peptides
Failed Back Surgery Syndrome
Paper Details
References
  • References45
  • Citations58
12345...
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