An Estimation of Lifetime Fatal Carcinogenesis Risk Attributable to Radiation Exposure in the First Year Following Polytrauma: A Major Trauma Center's Experience Over 10 Years

The Journal of Bone and Joint Surgery. American Volume
Anthony HowardPeter V Giannoudis

Abstract

The utilization of medical imaging continues to rise, including routine use in major trauma centers. The aims of this study were to estimate the amount of radiation exposure from radiographic imaging and the associated fatal carcinogenesis risk among patients treated for polytrauma at 1 institution. Included were patients who were admitted to our institution with an Injury Severity Score (ISS) of ≥16 during the period of January 2007 to December 2016. Records of patients were reviewed to assess exposures to radiation (excluding fluoroscopy) in the 12 months following injury. The risk of developing a fatal cancer of any type was modeled using patient age and sex, on the basis of the International Commission on Radiological Protection (ICRP) recommendations. Estimates of cancer risk were based on the exposure received and then imported into previously developed models. Overall, 2,394 patients, with a mean ISS of 28.66 (range, 17 to 66), were included in our analysis. The mean total radiation dose received was 30.45 mSv and the median dose was 18.46 mSv. One hundred and fifteen patients (4.8% of the cohort) received ≥100 mSv of radiation. The total patient group had a 3.56% mean risk of fatal carcinogenesis of any type that relate...Continue Reading

References

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Citations

Aug 21, 2020·Journal of Orthopaedic Trauma·Stephen GibbsGeoffrey S Marecek
Jul 4, 2020·The Journal of Bone and Joint Surgery. American Volume·Niloofar Dehghan, Michael D McKee
Oct 17, 2020·The Journal of Bone and Joint Surgery. American Volume·Peter S Rose
Feb 16, 2021·The Journal of Bone and Joint Surgery. American Volume·Corey J SchiffmanFrederick A Matsen
May 27, 2020·The Journal of Bone and Joint Surgery. American Volume·Niloofar Dehghan, Michael D McKee
Apr 25, 2021·BMC Pulmonary Medicine·Christopher R GilbertJed A Gorden
May 18, 2021·The Journal of the American Academy of Orthopaedic Surgeons·Harsh WadhwaMichael J Gardner

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