An ethical framework for responding to drug shortages in pediatric oncology

Pediatric Blood & Cancer
Jill C BeckJeremy R Garrett

Abstract

The frequency of drug shortages has increased considerably over the last decade. Important ethical issues arise whenever the supply of an effective drug is insufficient to meet demand. Using the ethical principles of beneficence, non-maleficence, and justice, institutions can guide prioritization of drug distribution before a shortage occurs to avoid unfair and unethical distribution of resources. This analysis will give a historical context for drug shortages, identify, and explore the central ethical concerns raised by drug shortages, and propose an ethical framework for addressing them in the context of pediatric oncology.

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Apr 15, 2011·Risk Analysis : an Official Publication of the Society for Risk Analysis·Kevin Haninger, James K Hammitt
Jan 10, 2012·The American Journal of Bioethics : AJOB·Philip M Rosoff
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Feb 4, 2014·Pediatrics·Matthew DecampUNKNOWN Working Group on Chemotherapy Drug Shortages in Pediatric Oncology
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Citations

Jul 22, 2015·Anesthesia and Analgesia·Danton S Char, David Magnus
Jan 31, 2016·Journal of the National Cancer Institute·Yoram UnguruSteven Joffe
Aug 30, 2017·World Journal of Clinical Oncology·Jill C BeckBruce G Gordon
Nov 20, 2016·Pediatric Blood & Cancer·Heidi V RussellStacey Berg
Nov 29, 2020·Journal of Medical Ethics·Zev M NakamuraDonald L Rosenstein
Jan 12, 2021·The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG·Jeffrey D MossShabnam Gaskari
Mar 5, 2019·Pediatric Emergency Care·Katie A DonnellyMaryann E Mazer-Amirshahi

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