An evaluation of hearing in infants administered with colistin in the premature neonatal intensive care unit

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Selman Sarıca, Sadık Yurttutan

Abstract

The aim of this study was to investigate the effects of colistin on hearing by evaluating the otoacoustic emission tests and clinical auditory brainstem responses in preterm infants treated with colistin in the neonatal intensive care unit. The study included 30 neonates (male: n = 16, female: n = 14) born before 37 weeks who were admitted to the Neonatal Intensive Care Unit at the Kahramanmaras Sutcu Imam Medical Faculty between January 2014 and January 2015 and who were treated with colistin during their time in intensive care because of infection. A control group was formed consisting of 30 preterm infants (male: n = 18, female: n = 12) with no additional disease born in the hospital during the same period. Following an ear, nose and throat examination the distortion product otoacoustic emission test, transient evoked otoacoustic emission and clinical auditory brainstem response tests were applied to all 60 patients. The otoacoustic emission responses obtained from the control group were positive and clinical auditory brainstem responses up to 15 dB were obtained. In the colistin group negative otoacoustic emission responses were obtained in two patients unilaterally and in one patient bilaterally and loss was observed at th...Continue Reading

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