An evaluation of patient self-testing competency of prothrombin time for managing anticoagulation: pre-randomization results of VA Cooperative Study #481--The Home INR Study (THINRS).

Journal of Thrombosis and Thrombolysis
Rowena DolorTHINRS Site Investigators

Abstract

Prior studies suggest patient self-testing (PST) of prothrombin time (PT) can improve the quality of anticoagulation (AC) and reduce complications (e.g., bleeding and thromboembolic events). "The Home INR Study" (THINRS) compared AC management with frequent PST using a home monitoring device to high-quality AC management (HQACM) with clinic-based monitoring on major health outcomes. A key clinical and policy question is whether and which patients can successfully use such devices. We report the results of Part 1 of THINRS in which patients and caregivers were evaluated for their ability to perform PST. Study-eligible patients (n = 3643) were trained to use the home monitoring device and evaluated after 2-4 weeks for PST competency. Information about demographics, medical history, warfarin use, medications, plus measures of numeracy, literacy, cognition, dexterity, and satisfaction with AC were collected. Approximately 80% (2931 of 3643) of patients trained on PST demonstrated competency; of these, 8% (238) required caregiver assistance. Testers who were not competent to perform PST had higher numbers of practice attempts, higher cuvette wastage, and were less able to perform a fingerstick or obtain blood for the cuvette in a ti...Continue Reading

Associated Clinical Trials

Mar 28, 2002

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Citations

Jan 25, 2013·Vascular Health and Risk Management·Caleb FergusonPatricia M Davidson
Nov 11, 2009·Journal of Thrombosis and Thrombolysis·Lynn B Oertel, Edward N Libby
Jan 14, 2016·BMC Medical Education·Caleb FergusonPatricia M Davidson
Mar 22, 2012·Rehabilitation Nursing : the Official Journal of the Association of Rehabilitation Nurses·Carolee Polek, Thomas Hardie
May 29, 2016·Journal of General Internal Medicine·Ciaran S PhibbsUNKNOWN writing for the THINRS Executive Committee and Site Investigators
Aug 16, 2014·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Caleb FergusonPatricia M Davidson
Apr 6, 2017·The Cochrane Database of Systematic Reviews·Danielle E ClarkesmithDeirdre A Lane
Apr 5, 2012·Clinical Chemistry·Kimberly M Lovett, Bryan A Liang

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