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An exactly solvable model of random site-specific recombinations

Bulletin of Mathematical Biology

Nov 16, 2012

Yi Wei, Alexei A Koulakov

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Abstract

Cre-lox and other systems are used as genetic tools to control site-specific recombination (SSR) events in genomic DNA. If multiple recombination sites are organized in a compact cluster within the same genome, a series of random recombination events may generate substantial cell specif...read more

Mentioned in this Paper

Sequence Inversion
Connectome
Genome
Neurons
Brain
Recombination, Genetic
Genomics
Neuronal
Genomic DNA
Mosaic Organism
1
Paper Details
References
  • References7
  • Citations2
1
  • References7
  • Citations2
1

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An exactly solvable model of random site-specific recombinations

Bulletin of Mathematical Biology

Nov 16, 2012

Yi Wei, Alexei A Koulakov

PMID: 23151958

DOI: 10.1007/s11538-012-9788-z

Abstract

Cre-lox and other systems are used as genetic tools to control site-specific recombination (SSR) events in genomic DNA. If multiple recombination sites are organized in a compact cluster within the same genome, a series of random recombination events may generate substantial cell specif...read more

Mentioned in this Paper

Sequence Inversion
Connectome
Genome
Neurons
Brain
Recombination, Genetic
Genomics
Neuronal
Genomic DNA
Mosaic Organism
1

Feeds With Similar Papers

Computation Neuroscience

Computation neuroscience employs models, statistics, simulations, and theoretical analyses to understand mechanisms that govern neural functions. Here is the latest research in this domain.

Related Papers

Nature Methods

One stem cell at a time

Nature MethodsDecember 8, 2011
Natalie de Souza
Cold Spring Harbor Protocols

Multicolor Brainbow imaging in zebrafish

Cold Spring Harbor ProtocolsJanuary 6, 2011
Y Albert PanAlexander F Schier
Paper Details
References
  • References7
  • Citations2
1
  • References7
  • Citations2
1

Download from

Publisher
PubMed
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