An examination of colorectal cancer burden by socioeconomic status: evidence from GLOBOCAN 2018.

The EPMA Journal
Rajesh Sharma

Abstract

Colon and rectum (colorectal) cancer cause substantial mortality and morbidity worldwide. The management and control of a complex disease such as cancer cannot rely on the old strategy of "one disease one medicine" and must make a transition into new-age practices involving predictive, preventive, and personalized medicine (PPPM) at its core. Adoption of PPPM approach to cancer management at the policy level requires quantification of cancer burden at the country level. For this purpose, we examine the burden of colorectal cancer in 185 countries in 2018. Based on results, we discuss the opportunities presented by PPPM and challenges to be encountered while adopting PPPM for the treatment and prevention of colorectal cancer. Age- and sex-wise estimates of colorectal cancer were procured from the GLOBOCAN 2018. The country- and region-wise burden of colorectal cancer in 185 countries was examined using all-age and age-standardized incidence and mortality estimates. Human development index (HDI) was employed as the indicator of socioeconomic status of a country. Mortality-to-incidence ratio (MIR) was employed as the proxy of 5-year survival rate. Globally, colorectal cancer claimed an estimated 880,792 lives (males 484,224; femal...Continue Reading

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Citations

Jul 18, 2020·Cancers·Jonadab E OlguínLuis I Terrazas
Nov 22, 2020·Life Sciences·Sepideh GhaniBahram Kazemi
May 25, 2021·Expert Review of Precision Medicine and Drug Development·Amanda N LisbyScott A Waldman
Nov 16, 2021·Cancer Causes & Control : CCC·Mohammad HajizadehRobin Urquhart

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Software Mentioned

MS Excel
Python
Stata
GLOBOCAN

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