An Examination of Pain Catastrophizing and Endogenous Pain Modulatory Processes in Adults with Chronic Low Back Pain

Pain Medicine : the Official Journal of the American Academy of Pain Medicine
Michael A OwensBurel R Goodin

Abstract

Research on chronic low back pain (cLBP) has focused heavily on structural abnormalities with emphasis on diagnostic imaging. However, for many cLBP patients, clinical pain and disability are not clearly associated with identifiable pathology of the spine or associated tissues. Therefore, alternative determinants such as psychological factors and dysfunctional pain modulatory processes have been suggested to be important. This observational study examined differences in pain catastrophizing and endogenous pain modulation between 25 cLBP patients and 25 pain-free controls. Associations among pain catastrophizing, endogenous pain modulatory processes, clinical pain reports, and disability were also examined in cLBP patients. Endogenous pain modulation was examined using temporal summation (TS) of mechanical and heat pain stimuli as well as conditioned pain modulation (CPM) with algometry (test stimulus) and the cold pressor task (conditioning stimulus). Findings demonstrated significantly greater pain catastrophizing as well as greater TS of mechanical and heat pain for cLBP patients compared with controls. CPM was not present in cLBP patients or controls. Among cLBP patients, pain catastrophizing was significantly associated wit...Continue Reading

References

Mar 1, 1997·The Clinical Journal of Pain·M E RobinsonF J Keefe
Nov 14, 2000·Spine·J C Fairbank, P B Pynsent
Feb 15, 2001·The New England Journal of Medicine·R A Deyo, J N Weinstein
Apr 6, 2001·The Clinical Journal of Pain·M J SullivanJ C Lefebvre
Oct 2, 2002·Annals of Internal Medicine·Jeffrey G Jarvik, Richard A Deyo
May 14, 2005·The Journal of Pain : Official Journal of the American Pain Society·Robert R EdwardsRoger B Fillingim
Apr 19, 2006·The Journal of Pain : Official Journal of the American Pain Society·Rob J E M SmeetsJ André Knottnerus
Jun 17, 2006·BMJ : British Medical Journal·B W KoesS Thomas
Jul 4, 2006·European Journal of Pain : EJP·Søren O'NeillLars Arendt-Nielsen
Aug 19, 2006·Annals of the Rheumatic Diseases·Daniëlle A W M van der WindtLex M Bouter
Feb 17, 2007·European Journal of Pain : EJP·Kevin E VowlesChristopher Eccleston
May 17, 2008·The Journal of Pain : Official Journal of the American Pain Society·Claudia M CampbellRoger B Fillingim
May 1, 2009·Expert Review of Neurotherapeutics·Phillip J QuartanaRobert R Edwards
Aug 18, 2009·Pain·Dennis A RevickiFrancis J Keefe
Aug 29, 2009·The Journal of Pain : Official Journal of the American Pain Society·Alban Latremoliere, Clifford J Woolf
Mar 17, 2010·European Journal of Pain : EJP·David YarnitskyOliver Wilder-Smith
May 5, 2010·The Journal of Pain : Official Journal of the American Pain Society·Claudia M CampbellRobert R Edwards
Dec 15, 2010·Neuroscience Letters·C G BachmannS Happe
Apr 1, 2011·Physical Therapy·Steven J Linton, William S Shaw
Mar 7, 2012·American Journal of Public Health·Lauren E GriffithLacey E Langlois
Jul 24, 2012·The Spine Journal : Official Journal of the North American Spine Society·Francisco M KovacsUNKNOWN Spanish Back Pain Research Network
Sep 18, 2012·The Journal of Pain : Official Journal of the American Pain Society·Gwyn N LewisPeter J McNair
Feb 2, 2013·The Clinical Journal of Pain·Sabine MlekuschMichele Curatolo
Dec 3, 2013·The Journal of Pain : Official Journal of the American Pain Society·Linda LeRescheMichael Von Korff
Mar 13, 2014·The Spine Journal : Official Journal of the North American Spine Society·Maria M WertliSherri Weiser
Apr 15, 2014·Arthritis & Rheumatology·Yenisel Cruz-AlmeidaRoger B Fillingim
May 3, 2014·The Journal of Pain : Official Journal of the American Pain Society·Richard A DeyoDebra K Weiner
Nov 29, 2014·AJNR. American Journal of Neuroradiology·W BrinjikjiJ G Jarvik

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Citations

Nov 26, 2019·The Clinical Journal of Pain·Y V Raghava NeelapalaLaura Frey-Law
Mar 25, 2020·Pain·Chika OkusoguLuana Colloca
Jun 13, 2019·Pain Practice : the Official Journal of World Institute of Pain·Pauline KuithanDeborah Falla
Mar 30, 2017·Pain Research & Management : the Journal of the Canadian Pain Society = Journal De La Société Canadienne Pour Le Traitement De La Douleur·Chloe J TaubBeth D Darnall
Nov 7, 2017·European Journal of Pain : EJP·L Arendt-NielsenA Mohr Drewes
Feb 24, 2018·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Laura D EllingsonDane B Cook
Aug 21, 2020·The Clinical Journal of Pain·Kasper S ChristensenThorvaldur S Palsson
Apr 9, 2021·The Clinical Journal of Pain·Thorvaldur S PalssonThomas Graven-Nielsen
Jun 16, 2021·Pain Management Nursing : Official Journal of the American Society of Pain Management Nurses·Lana Paula Cardoso MoreiraFuad Ahmad Hazime
Nov 21, 2021·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Marialuisa RausaDaniela Palomba

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