An excitatory basis for divisive normalization in visual cortex.

Nature Neuroscience
Tatsuo K SatoM Carandini

Abstract

Neurons in visual cortex are connected not only locally, but also through networks of distal connectivity. These distal networks recruit both excitatory and inhibitory synapses and result in divisive normalization. Normalization is traditionally thought to result from increases in synaptic inhibition. By combining optogenetic stimulation and intracellular recordings in mouse visual cortex, we found that, on the contrary, normalization is a result of a decrease in synaptic excitation.

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Citations

Nov 24, 2016·Nature Communications·Erin KochQasim Zaidi
Nov 26, 2016·Biological Psychiatry·David J HeegerIlan Dinstein
Jan 30, 2018·ELife·Michael-Paul SchallmoScott O Murray
Aug 12, 2018·Nature Communications·Jan ZimmermannKenway Louie
Oct 23, 2019·Proceedings of the National Academy of Sciences of the United States of America·David J Heeger, Wayne E Mackey
Aug 28, 2020·Proceedings of the National Academy of Sciences of the United States of America·David J Heeger, Klavdia O Zemlianova
May 5, 2017·Annual Review of Neuroscience·Alessandra AngelucciPaul C Bressloff
Aug 20, 2019·Journal of Vision·John M Foley
Sep 29, 2020·Frontiers in Neuroscience·Daniela CamilloJ Alexander Heimel
Nov 30, 2016·Frontiers in Systems Neuroscience·Laura Restani, Matteo Caleo
Jan 9, 2020·Nature Reviews. Neuroscience·Katie A Ferguson, Jessica A Cardin
Nov 25, 2020·Proceedings of the National Academy of Sciences of the United States of America·Douglas A RuffMarlene R Cohen
May 30, 2020·Neuroscience Research·Tatsuo K Sato
Jan 14, 2021·Nature Communications·Destinee A AponteHiroyuki K Kato
Aug 28, 2021·Trends in Neurosciences·Anderson Speed, Bilal Haider

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