PMID: 19143035Jan 15, 2009Paper

An expeditious synthesis of bruguierol A

The Journal of Organic Chemistry
Francisco J FañanásFélix Rodríguez

Abstract

A very simple strategy for the construction of 2,3-benzofused 8-oxabicyclo[3.2.1]octane derivatives is reported. This new process is based on a platinum-catalyzed tandem intramolecular hydroalkoxylation-hydroarylation reaction of aryl-substituted pentynol derivatives. This reaction has been applied in the key step of the total synthesis of bruguierol A, allowing the synthesis of this natural product in a very straightforward manner.

References

Mar 14, 2002·Journal of the American Chemical Society·Barry M Trost, Young Ho Rhee
Jun 19, 2003·Journal of the American Chemical Society·Barry M Trost, Young Ho Rhee
Aug 5, 2004·Journal of the American Chemical Society·Hua QianRoss A Widenhoefer
Feb 25, 2005·Planta medica·Li HanSusanne Grabley
Oct 27, 2005·Journal of the American Chemical Society·Itaru NakamuraYoshinori Yamamoto
Oct 27, 2005·Journal of the American Chemical Society·Alois Fürstner, Paul W Davies
Feb 25, 2006·Angewandte Chemie·José BarluengaFrancisco J Fañanás
Mar 9, 2006·Journal of the American Chemical Society·Emilie GeninVéronique Michelet
Jul 17, 2007·The Journal of Organic Chemistry·Dionicio Martinez Solorio, Michael P Jennings
Aug 28, 2007·Chemistry : a European Journal·Sivakolundu BhuvaneswariChien-Hong Cheng
Dec 7, 2007·Angewandte Chemie·Alejandro Diéguez-VázquezSteven V Ley
May 4, 1998·Angewandte Chemie·Charles M MarsonK M Abdul Malik

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Citations

Jan 5, 2012·Nature Chemistry·Bradley R BalthaserJohn K Snyder
Jun 23, 2012·Journal of the American Chemical Society·Yan MillerSherry R Chemler
Feb 26, 2015·Organic & Biomolecular Chemistry·Sachin HandaLeGrande M Slaughter
Jul 16, 2009·Chemistry : a European Journal·José BarluengaFrancisco J Fañanás
Jul 6, 2010·Chemistry : a European Journal·Abraham MendozaFrancisco J Fañanás
Apr 14, 2011·Organic & Biomolecular Chemistry·Benito AlcaideJosé Miguel Alonso
Apr 11, 2012·Angewandte Chemie·Francisco J FañanásFélix Rodríguez
May 15, 2010·Chemistry : a European Journal·José BarluengaFrancisco J Fañanás
Feb 5, 2021·Organic Letters·Alireza Abbasi KejaniBernhard Breit
Mar 3, 2018·The Journal of Organic Chemistry·Darunee SoorukramVichai Reutrakul
Aug 4, 2021·Chemistry : a European Journal·Santosh K Nanda, Rosy Mallik

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