Mar 1, 1989

An experimental model of cerebral venous hypertension in the rat

Neurologia Medico-chirurgica
Y KurokawaS Sasaki

Abstract

Several means of establishing a useful experimental model of cerebral venous hypertension were examined in rats. Retrograde embolization with an autologous blood clot passed through a catheter inserted in an external jugular vein, combined with ligation of the contralateral external jugular vein, was found to produce consistent, sustained cerebral venous hypertension. This model has the advantages of being technically easy to prepare, well tolerated by the animals, and suitable for autoradiographic and/or histochemical assessment of regional circulation and metabolism.

  • References
  • Citations1

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations1

Mentioned in this Paper

Metabolic Process, Cellular
Anastomosis, Surgical
August Rats
Brain
Structure of Jugular Vein
Metabolic Pathway
Hypertensive Disease
Blood Clot
Structure of External Jugular Vein
Cerebral Hemisphere Structure (Body Structure)

About this Paper

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.