An experimental paradigm for the prediction of Post-Operative Pain (PPOP).

Journal of Visualized Experiments : JoVE
Ruth LandauAlex Cahana

Abstract

Many women undergo cesarean delivery without problems, however some experience significant pain after cesarean section. Pain is associated with negative short-term and long-term effects on the mother. Prior to women undergoing surgery, can we predict who is at risk for developing significant postoperative pain and potentially prevent or minimize its negative consequences? These are the fundamental questions that a team from the University of Washington, Stanford University, the Catholic University in Brussels, Belgium, Santa Joana Women's Hospital in São Paulo, Brazil, and Rambam Medical Center in Israel is currently evaluating in an international research collaboration. The ultimate goal of this project is to provide optimal pain relief during and after cesarean section by offering individualized anesthetic care to women who appear to be more 'susceptible' to pain after surgery. A significant number of women experience moderate or severe acute post-partum pain after vaginal and cesarean deliveries. (1) Furthermore, 10-15% of women suffer chronic persistent pain after cesarean section. (2) With constant increase in cesarean rates in the US (3) and the already high rate in Brazil, this is bound to create a significant public hea...Continue Reading

References

Sep 30, 2005·Anesthesia and Analgesia·Brendan CarvalhoAlex Macario
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Citations

May 25, 2012·Archives of Gynecology and Obstetrics·Max DieterichBernd Gerber
Aug 28, 2010·Der Schmerz·A Schnabel, E Pogatzki-Zahn
Feb 6, 2013·Medical & Biological Engineering & Computing·Steven E HarteGrant H Kruger
Aug 15, 2013·Current Pain and Headache Reports·Yelena Granovsky
Nov 3, 2010·The Journal of Clinical Investigation·Michael H OssipovFrank Porreca
Jan 1, 2012·Scientifica·Michael H Ossipov
Jul 6, 2014·Best Practice & Research. Clinical Anaesthesiology·Andrea M Trescot
Dec 11, 2014·Pain Practice : the Official Journal of World Institute of Pain·Keiko Fujii-AbeHiroshi Kawahara
Aug 15, 2015·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Yelena GranovskyDavid Yarnitsky
Aug 9, 2013·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Marc O MartelRobert R Edwards
Jun 12, 2013·Annales Françaises D'anesthèsie Et De Rèanimation·V MartinezD Fletcher
Feb 18, 2012·European Journal of Pain : EJP·M BurgmerE Pogatzki-Zahn
Jun 28, 2015·The Journal of Pain : Official Journal of the American Pain Society·Ching-Hsia HungGary R Strichartz
Feb 24, 2015·BioMed Research International·Emilia Horjales-Araujo, Joergen B Dahl
Aug 27, 2013·The Journal of Urology·Timothy J NessRoger B Fillingim
Nov 26, 2013·Pain·David YarnitskyYelena Granovsky
Nov 8, 2016·Pain Research & Management : the Journal of the Canadian Pain Society = Journal De La Société Canadienne Pour Le Traitement De La Douleur·Alfonso Gil-MartínezJosué Fernández-Carnero
Jun 25, 2017·The Journal of Pain : Official Journal of the American Pain Society·Pascal Henri VuilleumierMichele Curatolo
Dec 10, 2019·Scandinavian Journal of Pain·Rania NuwailatiMark Drangsholt
Dec 21, 2018·Frontiers in Human Neuroscience·Yin Ying ChingJuan Zhou
Aug 6, 2019·Frontiers in Integrative Neuroscience·Tami Bar-ShalitaIrit Weissman-Fogel

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Methods Mentioned

BETA
cesarean section

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