An experimental study of the effects of Matricaria chamomilla extract on cutaneous burn wound healing in albino rats

Natural Product Research
Morteza Jarrahi

Abstract

Previous studies conducted on the anti-inflammatory, antimicrobial and antioxidant effects of Matricaria chamomilla (chamomile) extract led us to study the effect of topical chamomile extract on burn wound healing in albino rats. Thirty male albino rats (250-300 g) were randomly divided into three groups, as control, vehicle, and treatment. Second-degree burning was induced in 20% of whole surface area of animal body by placing the back of animal into boiling water for 8s. Animals of control group received no treatment. Animals of vehicle and treatment groups were treated topically by olive oil and extract dissolved in olive oil twice a day respectively from the first day of burn induction to complete wound healing. The percentage of wound healing was calculated weekly. The results showed that there was significant difference (p < 0.05) between vehicle and treatment groups. So we concluded that the chamomile extract in the form of rubbing oil had a good potential for acceleration of burn wound healing in rats.

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Citations

May 10, 2013·Bulletin of Experimental Biology and Medicine·A K KirichenkoA A Vlasov
Jun 5, 2014·Archives of Dermatological Research·Roodabeh BahramsoltaniRoja Rahimi
Oct 1, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Felipe Galeti MiguelAndresa Aparecida Berretta
May 28, 2019·BMC Veterinary Research·Milena TreschMichael Walkenhorst
Aug 26, 2020·Journal of Tissue Engineering and Regenerative Medicine·Parichehr Fatehi, Marjan Abbasi
Jan 20, 2011·International Journal of Dermatology·Hanem F KhaterReham S El-Madawy
Jul 17, 2018·TheScientificWorldJournal·Vânia Thais Silva GomesRenata Amadei Nicolau
Jul 19, 2019·Fitoterapia·Damaris Silva Dos SantosAdriana Gibara Guimarães
Mar 31, 2021·Journal of Equine Veterinary Science·Anis AnisYasmin Sadek
May 10, 2021·Daru : Journal of Faculty of Pharmacy, Tehran University of Medical Sciences·Somayeh NiknamTayebeh Toliyat
Aug 23, 2021·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Omid YazarluMaede Hasanpour

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