An exploration of patients' experiences of participation in a randomised controlled trial of the Manchester Acute Coronary Syndromes (MACS) decision rule

Emergency Medicine Journal : EMJ
Patricia Van Den BergRichard Body

Abstract

As an important part of a pilot study to determine the feasibility of a large randomised controlled trial (RCT) comparing use of the Manchester Acute Coronary Syndromes (MACS) decision rule with standard care, we aimed to explore patient attitudes and potential barriers to participation in a trial of this nature. We conducted a qualitative study nested within a pilot RCT comparing use of the MACS rule (which could enable some patients with chest pain to be discharged earlier) with standard care. Semi-structured interviews with consenting participants were conducted with reference to a bespoke topic guide. Interviews were audio recorded, transcribed verbatim and analysed using the Framework method with an inductive approach. The 10 interviewees expressed that participation in the trial was generally acceptable. All but one recommended participation to others. Participants who were in pain or anxious at the time of arrival reported that the initial invitation to participate in the trial was sometimes made too early. The approach was welcome, providing they had been given time to settle. Interviewees welcomed the opportunity that trial participation offered for them to play a more active role in their healthcare and to reduce unne...Continue Reading

References

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Apr 13, 2012·Circulation. Cardiovascular Quality and Outcomes·Erik P HessVictor M Montori
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Jan 14, 2016·Emergency Medicine Journal : EMJ·Joseph M BuckleySteve Goodacre
Jan 24, 2016·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Edward CarltonKim Greaves

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Citations

Oct 8, 2020·The Cochrane Database of Systematic Reviews·Catherine HoughtonLinda M Biesty

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