An extensively hydrolysed casein-based formula for infants with cows' milk protein allergy: tolerance/hypo-allergenicity and growth catch-up

The British Journal of Nutrition
C DupontCow's Milk Allergy Modified by Elimination and Lactobacilli study group

Abstract

Children with cows' milk protein allergy (CMPA) are at risk of insufficient length and weight gain, and the nutritional efficacy of hypo-allergenic formulas should be carefully assessed. In 2008, a trial assessed the impact of probiotic supplementation of an extensively hydrolysed casein-based formula (eHCF) on acquisition of tolerance in 119 infants with CMPA. First analysis of the study results showed that the studied formula allowed improvement of food-related symptoms. The scoring of atopic dermatitis (SCORAD) index was assessed at randomisation and after 6 months of feeding. A post hoc analysis was performed using WHO growth software's nutritional survey module (WHO Anthro version 3.2.2). All infants who were fed the study formula tolerated it well. The SCORAD index significantly improved from randomisation to 6 months of feeding with the study formula. Anthropometric data indicated a significant improvement in the weight-for-age, length-for-age and weight-for-length z scores, as well as in the restoration of normal BMI. The probiotic supplementation did not show any impact on these parameters. The present data showed that this eHCF was clinically tolerated and significantly improved the SCORAD index and growth indices.

References

Dec 1, 1988·The Journal of Allergy and Clinical Immunology·S A BockD D Metcalfe
Jan 1, 1993·Dermatology : International Journal for Clinical and Investigative Dermatology
Jun 17, 1998·The Journal of Pediatrics·E IsolauriM Kaila
May 8, 2001·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·B NiggemannE Isolauri
Aug 17, 2002·The Journal of Pediatrics·Delphine de Boissieu, Christophe Dupont
Jun 15, 2007·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Carlo AgostoniMarcello Giovannini
Sep 27, 2007·Archives of Disease in Childhood·Yvan VandenplasChristophe Dupont
Jan 3, 2008·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·B NiggemannU Wahn
Apr 26, 2008·The Journal of Allergy and Clinical Immunology·Jeroen HolUNKNOWN Cow's Milk Allergy Modified by Elimination and Lactobacilli study group
Apr 17, 2009·The American Journal of Clinical Nutrition·Peter RzehakUNKNOWN German Infant Nutritional Intervention Study Group
Dec 1, 2010·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·C DupontUNKNOWN Comité de nutrition de la Société française de pédiatrie
Jan 11, 2011·Allergy, Asthma & Immunology Research·Ha-Na ChoHye-Yung Yum
Nov 19, 2011·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C GoreA Woodcock
Mar 23, 2012·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Rosan MeyerNeil Shah
May 10, 2012·Journal of Pediatric Gastroenterology and Nutrition·S KoletzkoUNKNOWN European Society of Pediatric Gastroenterology, Hepatology, and Nutrition
Apr 1, 2010·The World Allergy Organization Journal·Alessandro FiocchiStefan Vieths
Aug 14, 2013·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·R MeyerN Shah
Mar 5, 2014·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·D LuytA T Clark
Jun 10, 2014·Allergy·A MuraroUNKNOWN EAACI Food Allergy and Anaphylaxis Guidelines Group

❮ Previous
Next ❯

Citations

Jan 23, 2016·Microbial Pathogenesis·Tal DrorMical Paul
Aug 30, 2018·The Journal of Dairy Research·Francisco Javier Espejo-CarpioEmilia María Guadix
May 24, 2020·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Agata StróżykHania Szajewska
Jun 27, 2019·Nutrients·Enza D'AuriaGianVincenzo Zuccotti
Jun 24, 2019·European Journal of Pediatrics·Sheeba QamerSanjay Patole
Aug 9, 2020·Allergologia et immunopathologia·M EslamiB Yousefi
Sep 4, 2019·Allergologia et immunopathologia·Stephanie Campos Dos SantosRenata Rodrigues Cocco

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.