An eye-tracker controlled cognitive battery: overcoming verbal-motor limitations in ALS

Journal of Neurology
Barbara PolettiVincenzo Silani

Abstract

We assessed language, attention, executive, and social cognition abilities in a sample of patients with Amyotrophic Lateral Sclerosis (ALS) by means of a recently developed cognitive battery based on oculomotor control with eye-tracking (ET) technology. Twenty-one ALS patients and 21 age- and education-matched healthy subjects underwent the ET-based cognitive assessment, together with the standard cognitive screening tools [Frontal Assessment Battery (FAB); Montreal Cognitive Assessment (MoCA); and Digit Sequencing Task]. Psychological measures of anxiety (State-Trait Anxiety Inventory-Y) and depression (Beck Depression Inventory) were also collected, and an ET usability questionnaire was administered. For patients, clinical and respiratory examinations were also performed, together with behavioural assessment (Frontal Behavioural Inventory). The developed battery discriminated among patients and controls with regard to measures of verbal fluency, frontal abilities, and social cognition. Measures of diagnostic utility confirmed a higher diagnostic accuracy of such ET-based tests with respect to FAB; similar diagnostic accuracy emerged when comparing them to the other standard cognitive tools (MoCA, WM). Usability ratings about ...Continue Reading

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Citations

Mar 4, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Ling TaoLi Feng
Mar 12, 2020·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Isabel K GosseltMichael A Van Es
Jun 3, 2020·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Enrica BersanoLetizia Mazzini
May 22, 2020·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Barbara PolettiVincenzo Silani
Jun 11, 2020·Geriatrics·David B Carr, Prateek Grover
Sep 16, 2019·Neuropsychologia·A P A BuenoM Hornberger

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