An fMRI Study of Concreteness Effects during Spoken Word Recognition in Aging. Preservation or Attenuation?

Frontiers in Aging Neuroscience
Tracy RoxburyDavid Copland

Abstract

It is unclear whether healthy aging influences concreteness effects (i.e., the processing advantage seen for concrete over abstract words) and its associated neural mechanisms. We conducted an fMRI study on young and older healthy adults performing auditory lexical decisions on concrete vs. abstract words. We found that spoken comprehension of concrete and abstract words appears relatively preserved for healthy older individuals, including the concreteness effect. This preserved performance was supported by altered activity in left hemisphere regions including the inferior and middle frontal gyri, angular gyrus, and fusiform gyrus. This pattern is consistent with age-related compensatory mechanisms supporting spoken word processing.

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Jun 1, 1984·Journal of Experimental Psychology. Human Perception and Performance·D A Balota, J I Chumbley
Sep 1, 1994·Psychology and Aging·U Lindenberger, P B Baltes
Jun 1, 1996·Computers and Biomedical Research, an International Journal·R W Cox
May 1, 1997·Neuropsychologia·M D'EspositoM J Farah
Jul 17, 1999·Human Brain Mapping·K A KiehlR D Hare
Dec 3, 1999·Brain : a Journal of Neurology·D PeraniF Fazio
Apr 25, 2000·Neuropsychologia·R J WiseS K Scott
Apr 17, 2001·The Behavioral and Brain Sciences·L W Barsalou
Jun 19, 2001·Psychology and Aging·S Kemper, A Sumner
Mar 22, 2002·NeuroImage·Murray GrossmanJames Gee
Jun 20, 2002·IEEE Transactions on Medical Imaging·L FreireJ F Mangin
Nov 5, 2002·NeuroImage·Roberto CabezaAnthony R McIntosh
Jun 27, 2003·Psychology and Aging·Paul Verhaeghen
Nov 5, 2003·Nature Reviews. Neuroscience·Mark D'EspositoAdam Gazzaley
Nov 15, 2003·Neuropsychologia·Christian J Fiebach, Angela D Friederici
Jan 8, 2004·Journal of Cognitive Neuroscience·Denise C ParkStephan F Taylor
Jan 27, 2004·NeuroImage·Joseph A MaldjianJonathan H Burdette
Mar 24, 2004·Cognition·P Indefrey, W J M Levelt
Apr 28, 2004·NeuroImage·Uta Noppeney, Cathy J Price
Aug 24, 2004·Proceedings of the National Academy of Sciences of the United States of America·Denise C ParkMason R Smith
Oct 12, 2004·Journal of Cognitive Neuroscience·Christine WhatmoughHoward Chertkow
May 17, 2005·NeuroImage·D S SabsevitzJ R Binder
Jun 16, 2005·NeuroImage·John Ashburner, Karl J Friston
Jul 19, 2005·Journal of Cognitive Neuroscience·J R BinderD A Medler
Jul 25, 2006·NeuroImage·K FliessbachB Weber
Nov 18, 2006·Journal of Neurophysiology·Arthur Wingfield, Murray Grossman
Jul 27, 2007·Journal of Cognitive Neuroscience·Penny M PexmanBradley G Goodyear
Sep 1, 2007·NeuroImage·John Ashburner
Apr 11, 2008·Annals of the New York Academy of Sciences·Cheryl L Grady
Apr 17, 2008·Current Directions in Psychological Science·Deborah M Burke, Meredith A Shafto
Mar 20, 2009·Journal of Cognitive Neuroscience·Marcus MeinzerBruce Crosson

❮ Previous
Next ❯

Citations

Jun 18, 2016·Journal of Cognitive Neuroscience·Jeremy B Caplan, Christopher R Madan
Apr 7, 2017·Frontiers in Psychology·Anna M Borghi, Annalisa Setti
Nov 5, 2019·Frontiers in Human Neuroscience·Heather D LucasKara D Federmeier
Feb 2, 2021·Frontiers in Psychology·Anna M BorghiLuca Tummolini

❮ Previous
Next ❯

Software Mentioned

WFU PickAtlas
INRIAlign
3dClustSim Analysis of Functional Neuroimages
Anatomy Toolbox
MarsBaR
DARTEL
SPSS Statistics
MATLAB
IBASPM

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.