An fMRI study of sentence-embedded lexical-semantic decision in children and adults.

Brain and Language
Erin Nicole Moore-ParksRalph-Axel Müller

Abstract

Lexical-semantic knowledge is a core language component that undergoes prolonged development throughout childhood and is therefore highly amenable to developmental studies. Most previous lexical-semantic functional MRI (fMRI) studies have been limited to single-word or word-pair tasks, outside a sentence context. Our objective was to investigate the development of lexical-semantic language networks in typically developing children using a more 'ecological' sentence-embedded semantic task that permitted performance monitoring while minimizing head movement by avoiding overt speech. Sixteen adults and 23 children completed two fMRI runs of an auditory lexical-semantic decision task with a button-press response, using reverse speech as control condition. Children and adults showed similar activation in bilateral temporal and left inferior frontal regions. Greater activation in adults than in children was seen in left inferior parietal, premotor, and inferior frontal regions, and in bilateral supplementary motor area (SMA). Specifically for semantically incongruous sentences, adults also showed greater activation than children in left inferior frontal cortex, possibly related to enhanced 'top-down' control. Age-dependent activation...Continue Reading

References

Aug 1, 1991·Brain : a Journal of Neurology·R WiseR Frackowiak
May 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S D FormanD C Noll
Jun 1, 1996·Computers and Biomedical Research, an International Journal·R W Cox
Nov 4, 1996·Neuroreport·D PeraniJ Mehler
Mar 14, 1998·Proceedings of the National Academy of Sciences of the United States of America·S E PetersenM E Raichle
Mar 31, 1999·The Behavioral and Brain Sciences·S R Quartz, T J Sejnowski
Mar 31, 2000·Trends in Cognitive Sciences·G Hickok, D Poeppel
Mar 15, 2001·Brain and Language·M W BurtonS L Small
Dec 10, 2002·Science·Ghislaine Dehaene-LambertzLucie Hertz-Pannier
Feb 25, 2003·Human Brain Mapping·William D GaillardCecile B Grandin
Jan 27, 2004·Neuron·Olaf HaukFriedemann Pulvermüller
Sep 30, 2004·Journal of Cognitive Neuroscience·Anja HahneAngela D Friederici
Oct 27, 2004·NeuroImage·Stephen M SmithPaul M Matthews
Jul 22, 2005·Human Brain Mapping·Jerzy P SzaflarskiAnna W Byars
Aug 16, 2005·Brain and Language·Henrike K BlumenfeldDouglas D Burman
Nov 9, 2005·NeuroImage·Tai-Li ChouNadia E Cone
Sep 14, 2006·Annual Review of Psychology·Alex Martin
Sep 11, 2007·International Journal of Audiology·Scott K HollandAnna W Byars
Oct 31, 2007·Neurology·W D GaillardW H Theodore
Feb 15, 2008·Journal of Cognitive Neuroscience·Jens Brauer, Angela D Friederici
Mar 7, 2008·Proceedings of the National Academy of Sciences of the United States of America·Damien A FairBradley L Schlaggar
Mar 13, 2008·Developmental Science·Elizabeth RedcayEric Courchesne
Apr 12, 2008·Cerebral Cortex·Michael D GreiciusRobert F Dougherty
Jul 1, 2008·NeuroImage·Elizabeth D O'HareElizabeth R Sowell
Dec 9, 2008·NeuroImage·Mark W WoolrichStephen M Smith
Apr 22, 2009·AJR. American Journal of Roentgenology·Jennifer VannestScott K Holland
Sep 1, 1998·Trends in Cognitive Sciences·J E Desmond, J A Fiez

❮ Previous
Next ❯

Citations

Jun 28, 2011·Psychological Research·Angela D FriedericiJens Brauer
Jan 15, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Erik C BrownEishi Asano
Jul 28, 2015·NeuroImage·Louise J Weiss-Croft, Torsten Baldeweg
Jul 6, 2016·Frontiers in Human Neuroscience·Barbara Tomasino, Michele Gremese
Jun 28, 2016·Neuroscience and Biobehavioral Reviews·Ingo HertrichHermann Ackermann
Aug 30, 2017·Frontiers in Behavioral Neuroscience·Yunqing LiPrasanna Karunanayaka
Apr 5, 2017·Applied Neuropsychology. Child·Julio César Flores-LázaroIgor I Stepanov
Jan 15, 2021·Scientific Reports·Teresa SylvesterArthur M Jacobs
Feb 1, 2021·Developmental Cognitive Neuroscience·Teresa SylvesterArthur M Jacobs
Jul 31, 2021·NeuroImage·Alexander EngeMichael A Skeide
Apr 19, 2020·NeuroImage·Alexander EngeMichael A Skeide

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cajal Bodies & Gems

Cajal bodies or coiled bodies are dense foci of coilin protein. Gemini of Cajal bodies, or gems, are microscopically similar to Cajal bodies. It is believed that Cajal bodies play important roles in RNA processing while gems assist the Cajal bodies. Find the latest research on Cajal bodies and gems here.

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.