An IL-1beta-dependent switch in innate mucosal immunity?

Immunity
James P Di Santo

Abstract

The mechanisms that guide the development of mucosal-associated innate lymphoid cells (ILCs) producing IL-17, IL-22, and IFN-gamma are the subject of intense interest. In this issue of Immunity, Hughes et al. (2010) identify a new role for IL-1beta in regulating an IL-22-producing ILC.

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