An illustrative overview of semi-quantitative MRI scoring of knee osteoarthritis: lessons learned from longitudinal observational studies

Osteoarthritis and Cartilage
Frank W RoemerAli Guermazi

Abstract

To introduce the most popular magnetic resonance imaging (MRI) osteoarthritis (OA) semi-quantitative (SQ) scoring systems to a broader audience with a focus on the most commonly applied scores, i.e., the MOAKS and WORMS system and illustrate similarities and differences. While the main structure and methodology of each scoring system are publicly available, the core of this overview will be an illustrative imaging atlas section including image examples from multiple OA studies applying MRI in regard to different features assessed, show specific examples of different grades and point out pitfalls and specifics of SQ assessment including artifacts, blinding to time point of acquisition and within-grade evaluation. Similarities and differences between different scoring systems are presented. Technical considerations are followed by a brief description of the most commonly utilized SQ scoring systems including their responsiveness and reliability. The second part is comprised of the atlas section presenting illustrative image examples. Evidence suggests that SQ assessment of OA by expert MRI readers is valid, reliable and responsive, which helps investigators to understand the natural history of this complex disease and to evaluate...Continue Reading

References

Feb 20, 2004·Osteoarthritis and Cartilage·C G PeterfyH K Genant
Jun 29, 2004·Skeletal Radiology·D SaddikM Richardson
Jun 6, 2006·Osteoarthritis and Cartilage·C G PeterfyR Stevens
Nov 4, 2008·Osteoarthritis and Cartilage·D T Felson, M C Nevitt
Jan 1, 2008·Annals of the Rheumatic Diseases·G Hernández-MolinaD T Felson
Mar 15, 2011·Osteoarthritis and Cartilage·D J HunterE Losina
Apr 25, 2012·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Jae-Ryong ChaKwang-Hwan Jung
Sep 8, 2012·Annals of the Rheumatic Diseases·Frank W RoemerUNKNOWN MOST study investigators
Jan 17, 2013·Nature Reviews. Rheumatology·Ali GuermaziDaichi Hayashi

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Citations

May 20, 2020·Radiology·Frank W RoemerAli Guermazi
Aug 17, 2019·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Ramon Castellanos, Sean Tighe
Dec 10, 2019·Rheumatology International·Kevin B HooverDan L Riddle
Feb 3, 2021·Journal of Vascular and Interventional Radiology : JVIR·Tijmen A van ZadelhoffEdwin H G Oei

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