An impedance threshold device increases blood pressure in hypotensive patients

The Journal of Emergency Medicine
Stephen W SmithJoseph Clinton

Abstract

The impedance threshold device (ITD-7) augments the vacuum created in the thorax with each inspiration, thereby enhancing blood flow from the extrathoracic venous systems into the heart. To the best of our knowledge, the ITD-7 has not previously been investigated in hypotensive patients in the emergency department (ED) or the prehospital setting. The objective of this study was to determine whether the ITD-7 would increase systolic arterial pressures in hypotensive spontaneously breathing patients. The ED study was a prospective, randomized, double-blind, sham control design. Patients with a systolic blood pressure ≤ 95 mm Hg were randomized to breathe for 10 min through an active or sham ITD. The primary endpoint was the change in systolic blood pressure measured non-invasively. The prehospital study was a prospective, non-blinded evaluation of the ITD-7 in hypotensive patients. In the ED study, the mean ± standard deviation rise in systolic blood pressure was 12.9 ± 8.5 mm Hg for patients (n = 16) treated with an active ITD-7 vs. 5.9 ± 5.9 mm Hg for patients (n = 18) treated with a sham ITD-7 (p < 0.01). In the prehospital study, the mean systolic blood pressure before the ITD-7 was 79.4 ± 10.2 mm Hg and 107.3 ± 17.6 mm Hg du...Continue Reading

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References

Jun 9, 2004·Autonomic Neuroscience : Basic & Clinical·Victor A ConvertinoWilliam H Cooke
Jul 9, 2004·Critical Care Medicine·Keith G LurieWolfgang G Voelckel
Aug 19, 2004·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Victor A ConvertinoKeith G Lurie
May 18, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Caroline A RickardsVictor A Convertino
Mar 1, 2008·Journal of Applied Physiology·Kathy L RyanVictor A Convertino

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Citations

Aug 13, 2013·Annales Françaises D'anesthèsie Et De Rèanimation·N SegalV A Convertino
Dec 18, 2013·Journal of Medical Engineering & Technology·Ismail CinelR Phillip Dellinger
Nov 1, 2017·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Victor A ConvertinoCharles J Lick
Mar 21, 2015·Circulation. Arrhythmia and Electrophysiology·Alfredo GamboaSatish R Raj
Nov 13, 2015·Anesthesia and Analgesia·Keith G LurieMichael Sweeney
Sep 29, 2012·The Journal of Trauma and Acute Care Surgery·Victor A ConvertinoDavid Lindstrom

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