PMID: 2500665Jul 1, 1989Paper

An improved chemiluminescence assay suggests non nitric oxide-mediated action of lysophosphatidylcholine and acetylcholine

Proceedings of the Society for Experimental Biology and Medicine
N K MenonR J Bing

Abstract

Using a new nitric oxide analyser, we have developed a sensitive chemiluminescence assay to detect trace quantities of NO in aqueous solutions. This improved technique in combination with the bioassay has been employed to verify the theory that NO released by vascular endothelium, accounts for the relaxation produced by acetylcholine, lysophosphatidylcholine and calcium ionophore A23187. Our results show that while calcium ionophore A23187 continuously released NO, acetylcholine and lysophosphatidylcholine relaxed vascular strips without releasing NO over the basal level.

Citations

Jan 1, 1994·Life Sciences·M SonodaY Sakagishi
Sep 28, 1994·Biochimica Et Biophysica Acta·S PouG M Rosen
Feb 1, 1996·Journal of Pharmacological and Toxicological Methods·Y IshidaK Momose
Oct 2, 2007·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Parveen RashidPhilip Bath
Sep 1, 1993·The Journal of Clinical Investigation·T OhigashiJ W Fisher
Nov 15, 1989·Biochemical and Biophysical Research Communications·S L ArcherE K Weir
Mar 13, 1999·Critical Care Medicine·S MehtaS Magder
Jul 6, 2000·Pediatrics International : Official Journal of the Japan Pediatric Society·F KotakeT Komoda
Jan 17, 2003·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Ian M BirdRonald R Magness
Nov 15, 1997·The American Journal of Physiology·X WangV M Miller
May 1, 1997·Analytical Biochemistry·M SonodaT Komoda

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