An improved method for the characterization of human haemoglobin mutants: identification of alpha-2-beta-2-95GLU, haemoglobin N (Baltimore)
No abstract listed.
The amino-acid sequence in the phenylalanyl chain of insulin. I. The identification of lower peptides from partial hydrolysates
Gene expression in an interspecific hybrid: analysis of hemoglobins in donkey, horse, and mule by peptide mapping
Probable evolutionary mechanism underlying octanol dehydrogenase isozyme patterns in the genus Drosophila
Rate of hemoglobin synthesis controlled at the translational level in differentiating erythroid cells from adult mice
Three cysteine residues in the alpha chain of rat haemoglobin (albino Rattus norvegicus): 13 (A 11), 104 (G 11) and 111 (G 18)
Hemoglobin Dakar = Hb Grady: demonstration by a new approach to the analysis of the tryptic core region of the alpha chain and oxygen equilibrium properties
Trimodality in the proportion of hemoglobin G Philadelphia in heterozygotes: evidence for heterogeneity in the number of human alpha chain loci
Interaction between cytochrome b5 and hemoglobin: involvement of beta 66 (E10) and beta 95 (FG2) lysyl residues of hemoglobin
Absence of beta-globin synthesis and excess of alpha-globin synthesis in homozygous beta-thalassemia
Excess of alpha-globin synthesis in homozygous beta-thalassemia and its removal from the red blood cell cytoplasm
Abnormal haemoglobins in Iran. Observation of a new variant--haemoglobin J Iran (alpha-2-beta-2 77 His--Asp)
Haemoglobin J Tongariki (alpha-115 alanine--aspartic acid): the first new haemoglobin variant found in a Pacific (Melanesian) population
Antenatal diagnosis of haemoglobinopathies by improved method of isoelectric focusing of haemoglobins
Hereditary persistence of foetal haemoglobin with beta-chain synthesis in cis position (Ggamma-beta+-HPFH) in a negro family
Occurrence of heterozygotes and homozygotes for the alpha-chain haemoglobin variant Hb-J(Tongariki) in New Guinea
Characterization of alpha23GluNH2 in hemoglobin Memphis. Hemoglobin Memphis/S, a new variant of molecular disease
Co-expression of mouse and rat haemoglobins in interspecific hybrids of mouse and at erythroleukemia cells
An improved method for electrophoretic characterization of globin chains from hemolyzates, purified hemoglobins, and fractions selected from chromatographic separations of chains
Hb Reims [alpha 2(23)(B4)Glu----Gly beta 2]: a new alpha chain variant with slightly decreased stability
Hb N-Baltimore [alpha 2 beta 2(95)(FG2)Lys----Glu] and Hb J-Iran [alpha 2 beta 2(77)(Ef1]His----Asp] observed in a Turkish family from Antalya
Absence of beta-globin synthesis and excess of gamma-globin synthesis in homozygous beta-thalassaemic subjects from the Ferrara region
Biosynthetic ratio of labelled globin chains in human reticulocytes, determined by electrophoresis on cellulose acetate
Amino acid composition of soluble tryptic peptides from aminoethylated beta-like chain of Rana esculenta homoglobin major component
Haemoglobin Saint Louis beta28 (B10) leucine leads to glutamine. A new unstable haemoglobin only present in a ferri form
Globin messenger in mouse leukemic cells: activity associated with RNA species in the region of 8 to 16 S
Bcr-Abl has a greater intrinsic capacity than v-Abl to induce the neoplastic expansion of myeloid cells
Distinction between two types of beta-thalassaemia by inducibility of the cell-free synthesis of beta-chains by nonthalassaemic soluble fraction
Methods for detection of hemoglobin variants and hemoglobinopathies in the routine clinical laboratory
A new technique involving a spherical stainless steel device to optimize positioning of the umbilicus
Trimodality in the percentages of beta chain variants in heterozygotes: the effect of the number of active Hbalpha structural loci
Hemoglobin Arlington Park. A new hemoglobin variant with two amino acid substitutions in the beta chain
Differences in affinity of variant beta chains for alpha chains: a possible explanation for the variation in the percentages of beta chain variants in heterozygotes
The structure of goat hemoglobins. V. A fourth beta chain variant (beta-D-Malta; 69 Asp is replaced by Gly) with decreased oxygen affinity and occurring at a high frequency in Malta
A new alpha chain variant, Hb Turriff [alpha 99(G6)Lys----Glu]: the interference of abnormal hemoglobins in Hb A1c determination
Two unstable hemoglobins in one individual: Hb Atlanta (beta 75 Leu leads to Pro) and Hb Coventry (beta 141 Leu deleted)
Hb N-Timone [alpha 2 beta 2(8)(A5)Lys----Glu]: a new fast-moving variant with normal stability and oxygen affinity
Two de novo mutations in one beta globin chain: hemoglobin Atlanta-Coventry, beta 75 Leu----Pro and beta 141 Leu deleted
Hemoglobin Miyashiro (beta 23[B5] val substituting for gly) an electrophoretically silent variant discovered by the isopropanol test
The Xmn1 polymorphic site 5' to the (G)gamma gene and its correlation to the (G)gamma:(A)gamma ratio, age at first blood transfusion and clinical features in beta-thalassemia patients from Western Iran
Globin-chain affinity chromatography on Sepharose-haptoglobin: a new method of study of hemoglobin synthesis in reticulocytes, in bone marrow and in colonies of erythroid precursors
Complete amino acid sequence of gamma chain of fetal hemoglobin of Japanese macaque (Macaca fuscata)
Globin chain synthesis analysis by high performance liquid chromatography in the screening of thalassemia syndromes
A severe hemolytic anemia related to a new case of hemoglobin Perth (Abraham Lincoln) in a French patient
A new unstable hemoglobin, Hb Yokohama beta 31 (B13)Leu substituting for Pro, causing hemolytic anemia
Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.
Genetic Screens in iPSC-derived Brain Cells
Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.
Alzheimer's Disease: MS4A
Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.
Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.
Chronic Fatigue Syndrome
Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.
Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.
Pharmacology of Proteinopathies
This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.
This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.
Alignment-free Sequence Analysis Tools
Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.